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LECTURE № 1. Immunodeficiency states in children. Clinic, diagnosis, treatment



Immunity is a way to ensure and maintain antigenic homeostasis.

Immunodeficiencies - a decrease in the functional activity of the main components of the immune system, leading to disruption of the body's antigenic homeostasis and above all to a decrease in the body's ability to defend against microbes, manifested in increased infectious morbidity.

Classification of immunodeficiency states:

1) primary immunodeficiency;

2) secondary immunodeficiencies.

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LECTURE № 1. Immunodeficiency states in children. Clinic, diagnosis, treatment

  1. LECTURE № 3. Cardiomyopathy in children. Clinic, diagnosis, treatment
    Classification of cardiomyopathy: 1) dilated (DCMP); 2) hypertrophic (hcmp); 3) restrictive (RCMP); 4) arrhythmogenic right ventricle
  2. LECTURE No. 4. Diseases of the pericardium in children. Clinic, diagnosis, treatment
    Clinical and morphological classification of pericardial lesions (A. A. Gerke, Z. M. Volynsky, E. E. Gogin). 1. Malformations of the pericardium (anomalies): 1) complete defects; 2) partial defects; 3) pericardial flaking defects (diverticula and cysts). 2. Pericarditis: 1) acute (dry fibrinous, exudative); 2) chronic (duration - 3 months); 3) adhesive (asymptomatic, squeezing, with
  3. LECTURE № 12. Malabsorption syndrome in children. Clinic, diagnosis, treatment
    Enteropathy is a pathological condition to which a lack or dysfunction of one or other intestinal enzymes results, due to the absence, deficiency or violation of the structure of one or other intestinal enzymes that provide digestive processes. Carbohydrate absorption: food carbohydrates consist of disaccharides: 1) sucrose (regular sugar = fructose + glucose), lactose (milk sugar =
  4. LECTURE № 16. Rheumatism in children and adolescents. Clinic, diagnosis, treatment
    Rheumatism is a systemic inflammatory disease of the connective tissue with a characteristic lesion of the heart. Etiology, pathogenesis. The main etiological factor in acute forms of the disease is b-hemolytic streptococcus group A. In patients with prolonged and continuously recurring forms of rheumatic heart disease, it is often not possible to establish the relationship of the disease with streptococcus. In the development of rheumatism special
  5. LECTURE № 15. Helminthiasis in children. Clinic, diagnosis, treatment, prevention
    Helminthiasis - a disease that develops when the parasitic worms-worms and their larvae are localized in the body. Classification of helminthiasis: 1) according to the biological principle: nematodoses (roundworms), cestodoses (tape), trematodoses (flukes); 2) epidemiological: geohelminthiasis, biohelminthoses,
  6. LECTURE № 7. Systemic vasculitis in children. Clinic, diagnosis, treatment
    Systemic vasculitis is a heterogeneous group of diseases with primary inflammatory and necrotic changes in the vascular wall. Etiology of systemic vasculitis: viruses (cytomegalovirus, hepatitis virus), bacteria (streptococcus, staphylococcus, salmonella), parasitic diseases (roundworm, filariasis). Classification of vasculitis. 1. Primary vasculitis with the formation of granulomas
  7. LECTURE № 5. Chronic heart failure in children. Clinic, diagnosis, treatment
    Heart failure is a condition in which the heart, despite an adequate flow of blood, does not provide for the body’s need for blood supply. Causes of chronic circulatory failure: a direct effect on the myocardium (toxic, infectious, traumatic), cardiovascular diseases. Classification. Classification of chronic heart failure (by
  8. LECTURE № 11. Modern problems of dysbiosis in children. Clinic, diagnosis, treatment
    Three phases of microbial colonization of the gastrointestinal tract in a child: 1) the first is aseptic, lasting from 10 to 20 hours; 2) the second - the initial settlement of microorganisms, the duration of from 2 to 4 days, depending on external environmental factors, the nature of nutrition and time of attachment to the chest; 3) the third - stabilization of microflora (up to 1 month). Intestinal microflora is complex, dynamically
  9. LECTURE No. 6. Disturbance of a warm rhythm at children. Clinic, diagnosis, treatment
    Arrhythmias are disorders of heart rhythm and conduction, occur in congenital heart defects, acquired heart diseases, dysfunction of the central and autonomic nervous system. Classification of cardiac arrhythmias. 1. Violation of the function of automatism - is to change the number of pulses rotating in the sinus node (violation of the formation of an excitation pulse): 1) nomotope violations
  10. LECTURE № 10. Chronic colon diseases in children. Clinic, diagnosis, treatment
    Chronic nonspecific diseases of the colon. 1. Functional disorders: 1) chronic constipation; 2) irritable bowel syndrome; 3) diverticular disease. 2. Organic disorders: 1) chronic colitis; 2) ulcerative colitis; 3) Crohn's disease; 4) intestinal amyloidosis. Classification of functional bowel disorders. 1. Intestinal upset: 1) irritable syndrome
  11. LECTURE № 13. Differential diagnosis of liver disease in children. Clinic, diagnosis, treatment
    Stage I: inspection. Anamnesis: the presence of liver damage is established Laboratory methods: (AlAT, AsAT, alkaline phosphatase, proteinogram, thymol, prothrombin index, bilirubin and urine urobiligen) - the diagnosis assumption. Hepatic parenchymal clearance of blood with technetium is the only or early sign of the disease (hepatitis, cirrhosis, amyloidosis). Ultrasound and liver scintigraphy with technetium (confirmation
  12. LECTURE № 9. Differential diagnosis of diffuse connective tissue diseases in children. Clinic, diagnosis, treatment
    Classification of rheumatic diseases. 1. Rheumatism. 2. Juvenile rheumatoid arthritis. 3. Ankylosing spondylitis. 4. Other spondyloarthropathies. 5. Systemic lupus erythematosus. 6. Vasculitis: 1) hemorrhagic vasculitis (Sheklein — Genoch); 2) periarteritis nodosa (polyarteritis in young children, Kawasaki disease, Wegener's disease); 3) Takayasu arteritis. 7. Dermatomyositis. 8. Scleroderma. 9.
  13. LECTURE № 17. Broncho-obstructive syndrome. Clinic, diagnosis, treatment. Respiratory failure. Clinic, diagnosis, treatment
    Broncho-obstructive syndrome is a clinical symptom complex observed in patients with a generalized violation of the patency of the bronchial passages, the leading manifestation of it is expiratory dyspnea, asthma attacks. Diseases accompanied by airway obstruction. The main causes of airway obstruction in children. 1. Obstruction of the upper respiratory tract: 1) acquired: a)
  14. LECTURE № 19. Respiratory diseases. Acute bronchitis. Clinic, diagnosis, treatment, prevention. Chronical bronchitis. Clinic, diagnosis, treatment, prevention
    LECTURE № 19. Respiratory diseases. Acute bronchitis. Clinic, diagnosis, treatment, prevention. Chronical bronchitis. Clinic, diagnosis, treatment,
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