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LECTURE No. 12. Malabsorption syndrome in children. Clinic, diagnosis, treatment



Enteropathy is a pathological condition that leads to a deficiency or impaired function of certain intestinal enzymes, due to the absence, deficiency or violation of the structure of certain intestinal enzymes that provide digestive processes.

Carbohydrate absorption: Food carbohydrates are composed of disaccharides:

1) sucrose (regular sugar = fructose + glucose), lactose (milk sugar = galactose + glucose);

2) monosaccharides: glucose and fructose;

3) plant starches (polysaccharide consisting of glucose molecules).

Enterocyte is not able to transport carbohydrates more than monosaccharide. Therefore, carbohydrates must be broken down before absorption. Malabsorption syndrome - a syndrome of impaired intestinal absorption, can result in malabsorption syndrome: a lack of pancreatic enzymes - a violation of the cavity phase of digestion; cholestasis, intestinal dysbiosis - a violation of the metabolism of bile acids, lipid transport to a violation of the biliary phase of digestion; deficiency of cavity enzymes (disaccharidases, peptidases, etc.
item) leads to a violation of membrane digestion; atrophy of the mucous membrane of the small intestine - to a violation of absorption, i.e., the cellulary phase of digestion, while membrane digestion also suffers; pathology of intestinal lymph flow, mesenteric circulation to - deterioration of further transport of absorbed substances - the outflow phase suffers; accelerated passage of food through the intestines - to the violation of all types of digestion.

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LECTURE No. 12. Malabsorption syndrome in children. Clinic, diagnosis, treatment

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