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Diseases of the female genital organs and mammary glands. Pathology of pregnancy.
Diseases of the female genital organs are divided into: 1) dishormonal; 2) inflammatory: 3) tumor. Among dishormonal diseases, glandular hyperplasia of the uterine mucosa and uterine pseudo-erosion are frequent. With glandular endometrial hyperplasia, its sharp thickening occurs due to polypous outgrowths. Histologically distinguish glandular-cystic and atypical hyperplasia, or diffuse adenomatosis. Endocervicosis (pseudo-erosion) of the cervix is located at the external uterine pharynx at the border of the stratified squamous epithelium of the cervix and the prismatic epithelium of its channel. Endocervicosis is represented by proliferation of high prismatic epithelium in the form of papillae (papillary pseudo-erosion) or glands (glandular pseudo-erosion). Due to the abundance of blood vessels, it has the appearance of a bright red spot, which creates an imitation of erosion. Atypical glandular endometrial hyperplasia and cervical endocervicosis are considered precancerous diseases. Inflammatory processes in the female genital organs are often a manifestation of the underlying disease (sepsis, tuberculosis, syphilis, gonorrhea). The most common endometritis, which can be acute and chronic. Among tumor diseases of the female genital organs, cancer of the cervix and uterus, as well as chorionepithelioma, is of great clinical importance. Pregnancy pathology includes eclampsia, ectopic pregnancy, spontaneous abortion, premature birth, cystic drift. After childbirth or abortion, a generic infection of the uterus, placental polyp, and chorionepithelioma may develop. Eclampsia is one of the types of toxicosis of pregnancy. The most severe changes are caused by a combination of generalized intravascular coagulation, with hemorrhages, massive necrosis with hemorrhages in the liver, mesangioproliferative glomerulonephritis with necronephrosis and hemorrhages. Hepatic-renal failure is becoming one of the leading causes of death. Bubble drift is a change in the placenta, hydropic and cystic transformation of chorionic villi, which is accompanied by proliferation of epithelium and syncytial cells. As a result, the villi turn into transparent vesicle-like formations resembling clusters of grapes. The ingrowth of altered villi into the thickness of the muscle layer of the uterus indicates a destroying cystic skid that can go into chorionepithelium. Dyshormonal diseases of the breast include its benign dysplasia (mastopathy, Reclus-Shimmelbusch disease), which is characterized by a violation of the differentiation of the epithelium, its atypism, a violation of the histostructure, but without invasion of the basement membrane and with the possibility of reverse development. Its occurrence is associated with an imbalance in estrogen balance. There are two main forms of mastopathy: non-proliferative and proliferative. Breast inflammation (mastitis) can be acute and chronic. Fibroadenoma is a benign breast tumor. It can be intraductal, intralobular and phyloid (leaf-shaped). The types of breast cancer include: a) non-infiltrating lobular cancer (lobular — cancer in place ”); b) non-infiltrating intraductal cancer (ductal cancer in place); c) Paget's disease.
Breast cancer produces both lymphogenous and hematogenous metastases, and relapses may also occur. Micropreparations 1. Intraductal fibroadenoma of the mammary gland (okr. GE). Designations: 1) slit-like glandular formations (“deer horns”); 2) proliferation of connective tissue around the ducts; 3) compression of the ducts of the mammary gland. 2. Chorionepithelial uterus (okr. GE). Designations: 1) tumor cubic cells of Langhans; 2) tumor cells of syncytium; 3) blood clots between tumor cells; 4) foci of hyalinosis. 3. Papillary cystadenoma of the ovary (okr. GE). Designations: 1) connective tissue capsule of a cyst; 2) papillary proliferation of the epithelial lining of the cyst; 3) plethora of blood vessels; 4) tissue atypism of the tumor. 4. Adenocarcinoma of the uterus (okr. GE). Designations: 1) atypism and polymorphism of the glands of the tumor tissue; 2) pronounced cellular atypism of the glandular epithelium; 3) invasive tumor growth. 5. Squamous cell carcinoma of the cervix with signs of keratinization (env. GE). Designations: 1) layers of atypical polymorphic squamous tumor cells; 2) keratinization foci (“cancerous pearls”); 3) invasive tumor growth. 6. Hyperplasia of the prostate gland (env. HE). Designations: 1) proliferation of glandular ducts; 2) cystic expanded glands; 3) fibromatous proliferation; 4) papillary proliferation of ductal epithelium; 5) adenoma capsule. 7. Adenocarcinoma of the prostate gland (okr. GE). Designations: 1) solid clusters of polymorphic glands; 2) pronounced cellular atypism of the glandular epithelium; 3) invasive tumor growth. 8. Placental polyp (okr. GE). Designations: 1) connective tissue organization of the polyp 2) proliferation of syncytium cells and Lanhgans cells 3) chorionic villi 4) foci of hyalinosis and hemorrhage. Macro preparations 1. Purulent endometritis. 2. Breast cancer. 3. Symptom - “retracted nipple” in breast cancer. 4. Teratoblastoma of the ovary. 5. Dermoid ovarian cyst. Test questions topics 1. Classification of diseases of the female genital organs. 2. Etiology, pathogenesis, morphology, complications and outcomes of dishormonal diseases of female genital organs. 3. Etiology, pathogenesis, morphology, complications, outcomes of inflammatory diseases of the female genital organs. 4. Etiology, pathogenesis, morphology, complications, outcomes of diseases associated with pregnancy pathology. 5. Histogenesis, morphology, complications of tumor diseases of the female genital organs. 6. Histogenesis, morphology, complications of dishormonal and tumor diseases of the mammary gland. Situational task A 45-year-old woman performed diagnostic curettage of the uterine mucosa in connection with heavy bleeding. A histological examination of the scraping revealed a large number of elongated sinuous glands. D hyperplasia of stromal cells. 1. What is the pathological process, its possible outcome. 2. What are the possible histological options for this process.
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Diseases of the female genital organs and mammary glands. Pathology of pregnancy.
- Diseases of the female genital organs and mammary glands. Cervical Diseases. UTERINE BODY DISEASES. Diseases of the fallopian tubes. DISEASES OF THE OVARIES. BREAST DISEASES
Diseases of the female genital organs and mammary glands. Cervical Diseases. UTERINE BODY DISEASES. Diseases of the fallopian tubes. DISEASES OF THE OVARIES. MILK DISEASES
- Diseases of the female genital organs and mammary glands.
1. The term "transformation zone" is understood to mean 1. healing endocervicosis 2. line of connection between ecto- and endocervix 3. anatomical border between the cervix and uterine body 2. Cervical intraepithelial neoplasia is a stage of development of cancer 1. fibrous 3. small cell 2. colloid 4. squamous 3. Types of endometrium giving rise to polyps 1. atrophic 2. functioning 3.
- HYPERPLASTIC, DYSTROPHIC AND TUMOR DISEASES OF THE FEMALE GENITAL ORGANS AND MAMMARY GLANDS
Hyperplastic and dystrophic processes of the female genital organs, as a rule, serve as one of the manifestations of the pathology of the endocrine and immune systems, as well as inflammatory processes of the genitals. They can also be induced by various environmental and hereditary factors. At the same time, hyperplastic and dystrophic changes often precede the development of malignant
- PATHOLOGY OF FEMALE GENITAL ORGANS, PREGNANCY, AND Puerperal
Diseases of the female genital organs are divided into dishormonal, inflammatory and tumor. The most important dishormonal pathological processes include glandular endometrial hyperplasia (GGE) and cervical erosion. ZhGE - a very common disease, occurs with ovarian dysfunctions [more often in menopause), ovarian tumors [tekoma, folliculoma) or excessive
- LESSON 8 TOPIC. Diseases of the female genital organs
Motivational characteristic of the topic. Knowledge of the morphological manifestations of diseases of the female genital organs is necessary for the successful assimilation of gynecological pathology at the Department of Obstetrics and Gynecology. In the practice of a doctor, this knowledge is necessary for the clinical anatomical analysis of sectional observations and for comparing clinical manifestations with the results of a biopsy study. Are common
- Diseases of the female genital organs
At the 4th week of pregnancy, primordial (initial) germ cells appear in the wall of the yolk sac. At 5-6 weeks, they migrate to the urogenital crest. Then the epithelium of this ridge, originating from the mesoderm leaf, proliferates and eventually forms the epithelium and stroma of future ovaries. However, for the complete formation of the ovaries, it is necessary to introduce into proliferate
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One of the negative phenomena of our modernity is the rapid increase in the frequency and number of sexually transmitted diseases. This is facilitated by changes in the orientation of sexual behavior of young people, the widespread use of contraceptives, the expansion of international tourism, prostitution, the resistance of pathogens to antibacterial agents and the absence of etiopathogenetic
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- ANATOMY OF FEMALE GENITAL ORGANS
The female reproductive system consists of the internal genital organs (internal genitalia) located in the pelvic cavity and the external genitalia (external genitalia) located outside the bone pelvis. The internal genital organs include the uterus, ovaries, fallopian tubes, and vagina. The external genitalia include the pubis, the labia minora, the labia minora, the vestibule of the vagina, and the clitoris. Pelvic cavity
- PATHOLOGY OF BREAST Glands OF ENDOCRINE GENESIS
Jean D. Wilson Breast examination is an important part of a medical examination. and often, by their condition, systemic pathology can be suspected, not only in women, but also in men. Therapists often neglect the examination of the mammary glands in men, and as for women, they prefer to shift this work to a gynecologist. Every doctor should be able to distinguish
- Female genital anatomy
The genitals of a woman are usually divided into external and internal. The external genitalia are the pubis, the labia minora and the labia minora, the clitoris, the vestibule of the vagina, and the hymen. Internal include the vagina, uterus, fallopian tubes, and ovaries. External genitalia The pubis is an area rich in subcutaneous fatty tissue that is covered in hairy maturity
- Female genital anatomy
The external genitalia are the pubis, the labia minora and the labia minora, the clitoris, the vestibule of the vagina, and the hymen. Internal include the vagina, uterus, fallopian tubes, and ovaries. The external genitalia. The pubis is an area rich in subcutaneous fatty tissue, at puberty, covered with hair, a triangular shape, the base facing up. Large
- MALIGNANT BREAST TUMORS AND PREGNANCY
Among malignant neoplasms in women, breast cancer is one of the first places. In recent years, the incidence of a combination of pregnancy and cancer has increased. There are two aspects of this problem: cancer among pregnant women and pregnancy with cancer. Breast cancer in pregnant women occurs in 0.03-0.3% of cases, pregnancy with breast cancer - in 0.78-3.8%, and in some reports
- INFLAMMATORY DISEASES OF FEMALE GENITAL ORGANS
The problem of inflammatory processes of the genitals has always been the focus of attention of obstetrician-gynecologists for the following reasons: • in frequency they occupy the first place in gynecology; • their consequences are very diverse and include various violations of the menstrual and reproductive functions (infertility, miscarriage, ectopic pregnancy), as well as general organ damage involving
- Genitals and mammary glands
Uterus. Immediately after the end of the third stage of labor, a significant contraction of the uterus occurs, which becomes spherical, somewhat flattened in the anteroposterior direction. Its bottom is 15-16 cm above the pubis. The thickness of the walls of the uterus, the largest in the bottom area (4-5 cm), gradually decreases towards the cervix, where the thickness of the muscles is only 0.5 cm. In the uterine cavity
- Female genital inflammatory diseases
Inflammatory diseases of the female genital organs (VZPO) occupy the first place in the structure of gynecological diseases. About 40% of gynecological patients in the hospital have VZPO. The cause of all inflammatory diseases of the genitals are microbes, which most often enter the body of a woman through sexual contact. Pathogens can also spread by the lymphogenous, hematogenous route,
- Surgery for anomalies in the development of female genital organs
Operations on female genital organs in connection with abnormalities of their development can be divided into the following groups: • operations on the external genital organs, hymen and vagina; • surgery for aplasia of the vagina; • operations with malformations of the uterus and
- Anomalies in the position of the female genital organs
The normal position of the female genital organs is ensured by a suspending, fixing and supporting ligamentous apparatus, mutual support and regulation of pressure by the diaphragm, abdominal press, and own tone (hormonal influences). Violation of these factors by inflammatory processes, traumatic injuries or tumors contributes to and determines their abnormal position.
- PATHOLOGY OF PREGNANCY. SPONTANEOUS ABORTION. ECTOPIC PREGNANCY. Gestosis. TROPHOBLASTIC DISEASE. PLACENTA PATHOLOGY
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