A.V. Pasechnik, E.G. Moiseeva, V.A. Frolov, G.A. Drozdova. Inflammation and metabolic disorders, 2011
Treatment of inflammatory periodontal diseases reduces the levels of such factors of cardiovascular risk, as C-reactive protein and fibrinogen, established by American scientists. This is another proof of the connection between periodontal diseases and cardiovascular pathology. C-reactive protein (CRP) and fibrinogen are acute-phase proteins and systemic markers of inflammation.
As it was stated at the 82nd general session of the International Association of Dental Research (Honolulu, Hawaii, USA), complex treatment resulted in a significant decrease in initially elevated concentrations of CRP (not less than 3 mg / L) and fibrinogen (not less than 3 g / l). The concentration of CRP and fibrinogen decreased by 9 months with mechanical treatment only, and by 6 months with the addition of an antibacterial drug (p <0.05).
Thus, in patients with elevated levels of CRP, the removal of plaque bacteria in combination with local antibiotic therapy reduced the concentration of CRP to the characteristic of low cardiovascular risk figures.
Today, we and many other authors develop effects of complex therapy on the levels of other markers of inflammation - cytokines, including effects on metabolic proaterogenic parameters.
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