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ANTHRAX

Anthrax (Siberian anthrax, malignant carbuncle) is an acute infectious disease belonging to the group of zoonoses, characterized by severe intoxication, fever, proceeding in the form of skin and visceral forms.

Clinical diagnosis

The incubation period from several hours to 8 days (an average of 2-3 days).

Skin form. In the case of the carbuncleous variety, a spot, papule, vesicle, pustule, ulcer, necrosis, regional lymphadenitis at the site of the entrance gate of infection. From the 2nd day of illness - intoxication with a rise in temperature to 39-40 ° C, cardiovascular disorders. The duration of intoxication is 5-6 days, the local process is 2-4 weeks. Edematous, bullous, erisepeloid varieties of the skin form are possible.

Pulmonary form. After a short incubation period (up to 1 day), a sudden rise in temperature to high numbers, runny nose, lacrimation, photophobia, chest pain, cough, intoxication, headache, vomiting, and increasing cardiovascular failure. Death.

Gastrointestinal form. Intoxication. Acute abdominal pain, bloody vomiting with bile, bloody diarrhea, intestinal paresis, inflammation of the peritoneum, effusion, perforation of the intestinal wall, peritonitis. Death in 2-4 days.

Septic form. The generalization of the process proceeds quickly without previous local phenomena. On the skin - profuse hemorrhages, the lungs, intestines are affected. Meningeal syndrome. Death occurs on the first day.

Laboratory diagnostics

1. The microscopic method. Examine for the presence of capsules smears prepared from the contents of vesicles or carbuncle stained by Gram.

2. Immunofluorescence method. Examine smears made from the above materials and treated with specific luminescent serum.

3. The bacteriological method. The material is examined (see above), seeded on a dense (MPA) and liquid (MPB) medium in order to isolate the pathogen.
For the same purpose, they put a bioassay by intraperitoneal infection of white mice. The material for the study can also be blood, sputum, feces, cadaveric material.

4. Allergic method. From the first days of the disease, they put a skin allergy test with anthraxin.

5. Detection of the pathogen antigen and antibodies to it by ELISA.

Activities for patients and contacts

Hospitalization. Obligatory, immediate - to the infectious ward or individual wards. For care, separate medical staff is allocated. All secretions are disinfected.

Isolation contact. Not carried out. For persons in contact with sick animals or who were in close contact with a sick person, establish medical supervision for 8 days. They are given emergency prophylaxis with anti-siren immunoglobulin and antibiotics.

Statement conditions. In the skin form - after epithelization and scarring of ulcers at the site of the fallen scab, in other forms - after clinical recovery.

Admission to the team. After clinical recovery.

Clinical examination: Not performed

Specific prophylaxis

1. The STI Siberian ulcer live dry vaccine for people conduct routine vaccinations according to professional indications by the cutaneous and subcutaneous method.

2. Antibiotic immunoglobulin and antibiotics provide emergency prevention of the disease in people who have had direct contact with infected material, no more than 5 days after eating infected food or after skin contact.

Nonspecific Prevention

Reducing and eliminating the incidence among domestic animals. Destruction of food and disinfection of raw materials obtained from sick animals.
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ANTHRAX

  1. ANTHRAX
    Anthrax (lat. - Febris carbunculosa; Eng. - Anthrax) is a particularly dangerous, acute septic disease of animals of many species and humans, caused by Bacillus anthracis, characterized by septicemia, damage to the skin, intestines, lungs, lymph nodes and death of diseased animals (see color paste). Historical background, distribution, hazard and damage. Anthrax known
  2. anthrax
    Anthrax (anthrax) is an exceptionally acute disease of all types of agricultural and wild animals, as well as humans, characterized by symptoms of sepsis, intoxication and the formation of various sizes of carbuncles on body parts, in most cases it ends in death. In recent years, anthrax is recorded as isolated cases, the last case of this
  3. anthrax
    Anthrax is a well-known animal disease that is transmitted to humans and proceeds as an acute infectious disease characterized by severe intoxication, damage to the skin and lymphatic apparatus. It got its name from the Greek word for “coal”, by analogy with the black color of the scab that forms when the skin form. Etiology. Causative agent of the disease
  4. Anthrax.
    The training target: using the algorithm, determine the clinical form of anthrax, conduct a differential diagnosis (see diagrams in the topic "Plague. Tularemia"); prescribe adequate treatment measures for emergency care and treatment at the hospital stage. Task for self-study. Using the textbook, Infectious Disease Manual, Lecture Material, and Recommended List
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  6. ANTHRAX
    Anthrax ? acute infectious disease characterized by fever, damage to the lymphatic apparatus, intoxication, proceeds in the form of a skin, rarely intestinal, pulmonary and septic form. The causative agent is an aerobic bacterium (extremely tenacious). Outside the human and animal body, it forms spores that are highly resistant to physico-chemical influences. A source
  7. ANTHRAX
    Infectious disease that occurs with symptoms of septicemia or with the formation of carbuncles of various sizes. From slaughtered animals, cattle, small horses, horses, camels and pigs are susceptible to the disease. Poultry in vivo does not suffer from anthrax. Wild animals are sick: moose, roe deer, reindeer, bears, wild boars, zebras, bison, elephants, etc. The disease is sick and
  8. anthrax
    Definition: Anthrax is an acute infectious disease of zoonotic origin from the group of infections of the external integument. Introduced into the group of especially dangerous infections. Pathogen: gram-positive motionless large stick Bacillus anthracis, aerob, optional anaerobic. In a susceptible organism, the vegetative form forms a capsule, in the environment with free oxygen
  9. anthrax
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  10. Anthrax.
    Infection of a person S. I. possibly contact, aerogenic, alimentary and transmission ways. Pathogenesis. Entrance gate - damaged skin, mucous membranes of the respiratory tract and gastrointestinal tract. Exotoxin causes protein coagulation, tissue edema, anthrax carbuncle develops - rec-necr ism, in the center of the focus is skin necrosis with the formation of a brown-black crust. Macrophages are recorded in reg l / nodes.
  11. anthrax
    Siberian
  12. anthrax (clinic, diagnosis, treatment)
    Anthrax (synonyms: malignant carbuncle) is an acute infectious disease that occurs predominantly in the form of a skin form, and pulmonary and intestinal forms are less common. Etiology: Bacillus anthracis - Gr + bacillus. Spores are stable in the environment for up to 10 years or more. Epidemiology: the source of the infection is domestic animals (cattle, sheep, goats, pigs). Infection path:
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  16. Peptic ulcer of the esophagus
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