home
about the project
Medical news
For authors
Licensed books on medicine
<< Previous Next >>

Coronarographic morphology of atherosclerotic lesions in acute coronary syndrome without ST segment elevation

The development of acute coronary syndrome is directly related to the complicated “growth of the atherosclerotic plaque, which is accompanied by the formation of blood clots of various sizes and localization with respect to the structure of the plaque.

The morphological composition of stable atherosclerotic plaques may vary in the ratio of structures that contribute to its stabilization or destabilization. With a sufficient amount to the plaque structure of functioning smooth muscle cells involved in the formation of connective tissue magrix. the plaque and its capsule constitute a strong stable formation. If the structure of the atrosclerotic plaque is dominated by elements that contribute to its destruction (inflammatory cells, foam cells, oxidized LGNP, localized in liid lakes), such a plaque is weak. predisposed to destruction.



Destruction of the plaque structure begins with the capsule. When destruction cells prevail in the capsule structure, especially macrophages synthesizing metalloproteinases, the collagen structure of the capsule becomes heterogeneous; its “weak spots” are formed, where a gap occurs, accompanied by contact of blood with thrombogenic tissues of the plaque and subsequent thrombosis.

Another cause of thrombosis is endothelial erosion. This variant of thrombosis is detected in approximately 30% of cases; more often in women. The blood clots resulting from this are not as massive as during the destruction of the capsule. Their main component is platelets, which, producing platelet-derived growth factor, contribute to the proliferation of smooth muscle cells and their migration into the plaque structure. With a small area of ​​erosion and a correspondingly small volume of a parietal thrombus, the processes of capsule reconstruction induced by smooth muscle cells prevail over the destruction processes.
<< Previous Next >>
= Skip to textbook content =

Coronarographic morphology of atherosclerotic lesions in acute coronary syndrome without ST segment elevation

  1. Tactics of percutaneous coronary intervention in acute coronary syndrome without ST segment elevation
    Recently published reviews indicate that percutaneous coronary interventions are performed in less than 50% of patients with acute coronary syndrome without ST elevation (GRACE (Global Registry of Acute Coronary Events), CRUSADE (Coronary Revascularization UltraSound Angioplasty DEvice trial)). Proponents of drug treatment for patients with unstable angina and myocardial infarction without ST segment elevation
  2. Percutaneous coronary interventions in acute coronary syndrome without ST elevation
    Percutaneous coronary interventions in acute coronary syndrome without segment elevation
  3. Determining the risk of rapid disease progression in acute coronary syndrome without ST segment elevation
    The importance of dividing patients with unstable angina and myocardial infarction without ST segment elevation into high and low risk groups for complications is justified by the fact that the clear advantage of performing early coronary angiography and, if necessary, percutaneous coronary intervention is determined only in patients at high risk for complications. In the recommendations of the European Cardiology
  4. Clinical protocol for providing medical care to patients with acute coronary syndrome without ST segment elevation (MI without Q wave and unstable angina)
    Heading for ICD-10: 120-122. Signs and criteria for diagnosing the disease Acute coronary syndrome is a group of symptoms and signs that make it possible to suspect acute myocardial infarction or unstable angina. The term "acute coronary syndrome" is used at the first contact with patients as a preliminary diagnosis. Acute coronary syndrome with persistent elevation of the ST segment on an ECG and without
  5. Acute coronary syndrome without ST segment elevation
    395. FOR THE DIAGNOSTICS OF CHD ITS CAN BE USED 1) radionuclide ventriculogafia 81 2) perfusion myocardial scintigraphy under physical exertion 3) ECG recording under physical exertion, transesophageal electrocardiostimulation 4) Holter monitoring ECGROSTI CEREME 5) PLAINS DO NOT
  6. Acute coronary syndrome without ST segment elevation
    395-5396-4397-4398-599-3-400-5-401-2402-5403-5404-1405-2406-5407-5408-4409-3,410-3,411-3 3 412- 3 413-4 414-5 415-4 416-4 417-2 418-
  7. 2.4. ACUTE CORONARY SYNDROME WITHOUT ST SEGMENT LIFT (ACS BP ST)
    If in the next 48 hours the patient suffered a prolonged (more than 15 minutes) pain attack, which makes the development of ACS suspect, emergency hospitalization is indicated, preferably in the ICU. If the first or progressive angina pectoris is diagnosed for the first 48 hours, hospitalization in the cardiology department is indicated. Management tactics: • Aspirin (Table 0.5 g) at 0.025-0.5 g
  8. ACUTE CORONARY SYNDROME WITHOUT SUSTAINABLE ST SEGMENT ELEVATION
    ACUTE CORONARY SYNDROME WITHOUT SUSTAINABLE SEGMENT ELEVATION
  9. NORMAL AND CORONAROGRAPHIC ANATOMY OF THE CORONARY ARTERIES. CORONAROGRAPHIC PROJECTIONS
    Blood supply to the human heart is carried out by three practically equivalent vessels. These are the anterior interventricular and envelope branches of the left coronary artery, which are formed during recalibration of the trunk of the left coronary artery, as well as the right coronary
  10. Percutaneous coronary interventions in the presence of bends in the bed of the coronary arteries, lesions of the mouth, calcified lesions, long lesions
    Percutaneous coronary interventions in the presence of bends in the bed of the coronary arteries, lesions of the mouth, calcified lesions, long
  11. Percutaneous coronary interventions in single discrete lesions of the coronary arteries, diffuse stenosis, multivascular lesion in coronary artery disease
    Percutaneous coronary interventions with single discrete lesions of the coronary arteries, diffuse stenosis, multivascular lesion with
  12. Interventional treatment of acute coronary syndrome with ST segment elevation
    Interventional treatment of acute coronary syndrome with segment elevation
  13. Clinical protocol for providing medical care to patients with acute coronary syndrome with ST segment elevation (MI with Q wave)
    ICD-10 rubric: I21-I22 Symptoms and criteria for diagnosing the disease Acute coronary syndrome with persistent ST elevation in most cases precedes acute myocardial infarction with Q wave. Acute myocardial infarction is necrosis of any myocardial mass due to acute prolonged ischemia. Clinical diagnostic criteria should be considered: - protracted (more than 20 min) anginal pain at rest; - the presence of typical
  14. Correction methods for acute respiratory failure in acute lung injury / acute respiratory distress syndrome with a proven effect on mortality and fan-induced lung damage
    • ???? Ventilation with small respiratory volumes. The use of small tidal volumes can reduce the manifestations of volumotrauma and avoid high transpulmonary pressures. According to the largest multicenter randomized controlled trial conducted by ARDSnet in 41 centers and involving 861 patients, the use of small tidal volumes (6 ml / kg body weight) leads to
  15. Percutaneous coronary interventions for a single-vascular lesion in IHD and single discrete stenoses
    From the moment the first coronary angioplasty was performed, the main coronarographic indications for this intervention were determined. The injuries suitable for balloon angioplasty included single proximal hemodynamically significant discrete non-calcified stenoses in patients with preserved LV function. Similar lesions, according to modern research, and
Medical portal "MedguideBook" © 2014-2019
info@medicine-guidebook.com