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Drug substance

The drug substance is the active principle of the drug.

Medicinal substances are obtained by chemical synthesis from medicinal raw materials through its special processing, as well as by biotechnological-logical methods, including gene and cell engineering.
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Drug substance

  1. GENERAL INFORMATION ABOUT MEDICINAL PLANTS BIOLOGICALLY ACTIVE SUBSTANCES OF MEDICINAL PLANTS, CAUSING THEIR PURPOSE
    The use of medicinal plants in practice is due to the presence in their composition of biologically active substances, which, when introduced into the body even in very small quantities, cause a certain physiological effect. These active substances are synthesized by the plants themselves from inorganic mineral substances of the soil, water, and carbon dioxide from the air. Synthesis is carried out by plants under the influence of
  2. Doses of drugs
    Commercially available dosage forms are usually packaged as single doses for humans. To determine the doses of most medicines, animals assume that the dose for a dog is half the human dose. However, this calculation is not always correct, therefore, in tables 3 and 4, the doses of drugs are given, taking into account the pharmacokinetics of drugs. Doses of medication always
  3. The interaction of drugs with food
    When studying the safety issues of using drugs, special attention is usually paid to their interaction with the components that make up food (Viktorov, AP et al., 1991, 2000). At the level of absorption of drugs in the gastrointestinal tract, the effect of food can be associated with: ¦ the formation of complexes with drugs, a change in the pH of the stomach and / or duodenum;
  4. Interaction at the stage of distribution of medicinal substances
    Medicinal substances of systemic action from the injection enter the blood. In the blood, they interact with plasma proteins and formed elements. As a result, free and bound drug fractions are formed (Table 5.7), which leads to a change in the rate of its metabolism and elimination, and in some cases to a change in the distribution pattern in organs and tissues.
  5. Medicinal substances
    Diarrhea is a frequent side effect of many drugs. The mechanisms of diarrhea in most cases are explainable, for example, when taking magnesium-containing antacids or phosphorus-containing substances, but in some cases the genesis of diarrhea is not clear enough. Substances such as sorbitol, mannitol, xylitol, lactulose, directly cause osmotic diarrhea. Colchicine, quinidine, quinine,
  6. Abstract. Methods for introducing drugs, 2010
    Subcutaneous injections Intramuscular injections Intravenous injections Intraosseous injections Intraperitoneal administration Intraoral and intrapulmonary methods of administering drugs Autohemotherapy Bleeding Intratracheal administrations Scar puncture and the introduction of drugs into
  7. Pathology caused by taking drugs
    Pathology caused by taking drugs is expressed in adverse drug reactions that develop in response to taking a drug for treatment, diagnosis or prophylaxis at the usual dosage. In Russia, the terms "drug disease", "drug pathology" are common, which are included in the broader concept of "iatrogenic pathology" (iatrogenic from Greek. Iftros is a doctor and
  8. The actual processes of obtaining medicinal substances.
    This technological stage of obtaining drugs is characterized by a large variety of technological processes and operations, equipment used and chemicals. Significant share in the industrial synthesis of intermediates and medicinal substances is occupied by processes associated with the replacement of hydrogen atoms in the core of aromatic compounds by certain groups.
  9. Puncture of the rumen and the introduction of medicinal substances in the book
    This manipulation is carried out in acute timpanii, when other methods of providing medical care have not given effect and there is a threat of death of the animal from asphyxiation. Before the scar is punctured, an operative field is prepared in the area of ​​the left hungry fossa. The scar is pierced with a trocar at a point lying in the middle of the line connecting the maclock with the middle of the last rib, or at the intersection of two hands attached
  10. CALENDULA MEDICINE (MEDICINE HANDLES) - CALENDULA OFFICINALIS L.
    Botanical characteristics. Compositae family. Annual light green herb. Taproot, branched. Stem erect, covered with glandular hairs, branched at base, up to 50-60 cm tall. Leaves are alternate, lower petiolate, upper sessile, obsolete-prominent. The flowers are collected in large baskets, yellow or orange-yellow. It blooms from June to deep
  11. GALEGA MEDICINAL - (KOZLYATNIK MEDICINE) - GALEGA OFFICINAL1S L.
    Botanical characteristics. Bean family. Perennial herbaceous plant. Taproot, weakly branching, with a short many-headed rhizome. Stems are numerous, erect, branched, up to 90 cm high, rarely up to 1.5 m. Leaves with stipules, pinnate, 5–20 'cm long. Flowers numerous light blue or pale purple, collected in dense, axillary brush. Seeds
  12. Dosing of drugs. Pharmacokinetics and pharmacodynamics of drugs
    The form of release of a medicinal substance largely determines its route of administration into the body. After the drug enters the body at the same time, two processes begin: • A change in the concentration of the drug substance over time. These processes are quantitatively described by pharmacokinetics. • Drug interaction with molecular targets of action in organs and tissues
  13. Delirium not caused by alcohol or other psychoactive substances. Abstinence with delirium associated with the use of psychoactive substances
    Code for ICD-10 Delirium, not caused by alcohol or other psychoactive substances F05 F10- F19 Abstinence with delirium, associated with the use of psychoactive substances F10.4, F11.4 F12.4 F13.4 F14.4 F15.4 F16.4 F17.4 F18.4 F19.4 Diagnosis When making a diagnosis Mandatory Level of consciousness, pupil size, neurological status, symptoms of affection
  14. Medicine
    In accordance with the Law of Ukraine “On Medicinal Products” (1996), medicinal products mean “substances or their mixtures of natural, synthetic or biotechnological origin, used to prevent pregnancy, prevent, diagnose and treat patients or change the state and function of the body”. The drug in pharmacology is called
  15. Types of drug interactions
    The following types of drug interactions are distinguished (AP Viktorov et al., 1991: AP AP Viktorov. 2000; MA Paltsev et al. 2005; Dsrimsdvsl LV et al. 2006): • pharmaceutical associated with physicochemical interactions of medicinal substances outside the body (for example, the formation of insoluble compounds): • pharmaceutical, associated with changes in fzrmakokineticheskie
  16. The main types of dosage forms
    All medicines are manufactured and marketed to the pharmaceutical market in a specific dosage form - that is, the form given to the drug substance (s) in a convenient for practical use condition that achieves the desired therapeutic or prophylactic effect. Dosage form - method of release of the drug. Medicines include
  17. Dosage Forms
    Drugs are used in various dosage forms. Dosage forms can be solid, liquid, soft. 1. Solid dosage forms include powders, powders, tablets, pills, pills, capsules, granules, and fees. Powders are called bulk solid dosage forms for internal and external use. Powders are simple (consisting of one
  18. Dosing of drugs
    Dose - the amount of medicinal substance, which is assigned to the animal at one time (one-time), per day (daily), the course of treatment (course). The dose of the drug substance is determined by a number of factors, the main of which are: the type of animal, the age of the animal, the mass of the animal, the method of administration of the drug. Depending on the type of animal, the dose of most
  19. Medicinal Anaphylactic Shock
    Drug anaphylactic shock is an acute generalized immediate-type allergic reaction that occurs when a drug is reintroduced into the body, which results in the release of mediators causing life-threatening disorders of important organs and systems (obstruction of the upper respiratory tract, hypotension, shortness of breath, fainting, etc. .). Drug
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