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Prevention of sudden cardiac death in patients with heart failure and the use of antiarrhythmic drugs

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Prevention of sudden cardiac death in patients with heart failure and the use of antiarrhythmic drugs

  1. Sudden cardiac death and its mechanisms in patients with heart failure
    As mentioned above, up to 50% of patients with heart failure do not survive to the final stage of heart decompensation, but die suddenly, often against the background of a stable clinical and hemodynamic state. In most (> 80%) cases, sudden cardiac death occurs due to the occurrence of high-grade ventricular arrhythmias, which, as a rule, are asymptomatic in heart failure. Found that the main
  2. Prevention of sudden cardiac death in patients with myocardial "bridges"
    Myocardial "bridges" consist of fibro-muscular legs that cover the epicardial coronary arteries at different levels. The presence of myocardial "bridges" according to angiography is noted in 0.5-4.5% of cases. The left anterior descending artery is almost always affected. A typical angiographic manifestation is systolic narrowing of the vessel due to transient myocardial compression. Though
  3. Prevention of sudden cardiac death in HCM
    HCMP is a common heart disease, the prevalence of which among adults is 1: 500. Sudden unexpected death with this disease is the most formidable consequence that occurs at different periods of life, but especially often at a young age and in patients without symptoms of the disease. The main task of cardiologists is to identify a small
  4. Prevention of sudden cardiac death in various clinical conditions
    Given that most cases of sudden cardiac death occur outside of clinics where appropriate conditions for resuscitation can be provided, the probability of rescue of these patients is very low. In addition, even after successful resuscitation, the possibility of a repeated episode of sudden cardiac death throughout the year in those not receiving adequate therapy
  5. Risk of sudden cardiac death in patients with unstable angina
    In Ukraine, 1997-2001 at the Institute of Cardiology. N.D. Strazhesko AMS of Ukraine, a prospective 4-year study was conducted to identify independent risk factors for sudden cardiac death in patients who had unstable (progressive) angina pectoris. During the observation, 44 of 392 patients developed sudden cardiac death. After multivariate regression
  6. Sudden Cardiac Death Prevention: General Approaches
    Primary prevention of sudden cardiac death in patients with coronary heart disease. According to the concept of P. Kumel’s triangle, the conditions for the formation of sudden cardiac death in patients with coronary artery disease are interrelated factors: 1) the presence of a sensitive myocardium (whose components are residual ischemia, electrical instability and LV dysfunction); 2) the effect of various triggers (tachycardia,
  7. Prevention of sudden cardiac death in DCMP
    DCMP is a chronic heart muscle disease characterized by dilatation of the left ventricle and impaired systolic function. Epidemiological studies found that the detection rate is about 20 cases / 100 thousand people per year, the prevalence is 38 cases / 100 thousand people per year. In 40% of cases, a family history is possible with a predominance of an autosomal dominant type of inheritance,
  8. Prevention of sudden cardiac death in disorders of the cardiac conduction system
    Sudden cardiac death may result from bradyarrhythmias in 15–20% of cases. If conduction disturbance is caused by an irreversible structural abnormality in patients with conduction disturbance, then sudden cardiac death can be caused by ventricular tachyarrhythmia. A heart rate driver certainly improves the condition of patients with bradyarrhythmias and can reduce mortality. Recommendations for
  9. Prevention of Sudden Cardiac Death with WPW Syndrome
    The prevalence of WPW syndrome is 0.1-0.2%. Its presence can lead to sudden cardiac death. This happens if paroxysm of atrial fibrillation causes very fast ventricular activation through an additional AV pathway with a short anterograde refractory period and provokes ventricular fibrillation. Sudden cardiac death in WPW syndrome - rare but dramatic
  10. Prevention of sudden cardiac death in aortic stenosis
    Aortic stenosis can be a congenital pathology, as well as acquired after an acute rheumatic attack or as a result of an age-related degenerative process (senile aortic stenosis). Usually, the history of aortic stenosis is characterized by a long asymptomatic period during which the degree of stenosis increases. In 1968, Ross and Braunwald showed that the risk of sudden cardiac death in
  11. Prevention of sudden cardiac death with a "sports heart"
    Anomalies of the cardiovascular system in many athletes are an increase in LV mass, cavity, wall thickness, or a combination of these factors. The cardiovascular causes of sudden cardiac death in athletes vary significantly depending on age. Over the age of 35 years, the predominant cause of death is CHD. Conversely, for athletes under the age of 35, the main reason
  12. Prevention of sudden cardiac death with arrhythmogenic pancreatic dysplasia
    Arrhythmogenic pancreatic dysplasia or right ventricular cardiomyopathy is a myocardial disease characterized by focal or global fibrous pancreatic myocardial changes with / without an increase in LV and with preservation of the thickness of the interventricular septum. The prevalence of this disease is completely unknown, approximately within the range of 1: 1 thousand -1: 10 thousand of the population. For this pathology is characteristic
  13. Prevention of sudden cardiac death with mitral valve prolapse
    Mitral valve prolapse is a fairly common valve leaf pathology with fuzzy echocardiography criteria. After clarification of its echoCG criteria, the prevalence of this pathology decreased markedly. Recent data from the Framingham study demonstrated that in the non-randomized group of outpatients, the prevalence of mitral valve prolapse was 1-3% at 3491
  14. Prevention of sudden cardiac death with abnormal coronary artery discharge
    Anomalies of the coronary arteries are rare. The prevalence of these anomalies in the general population is unknown. According to various sources, they are detected in 0.3-1.2% of patients who underwent coronary angiography. The most common coronary anomaly is a. сircumflaha (as a rule, the vessel departs from the right coronary sinus). No adverse events were noted in this group. However, the beginning of the left coronary artery from the right or
  15. Primary prevention of sudden cardiac death in "truly electric" heart diseases
    In patients with “truly electric” phenomena, in which the likelihood of sudden cardiac death is increased, the appropriateness of primary prophylaxis causes much less doubt and discussion than in patients with coronary heart disease complicated by ventricular
  16. Prevention of sudden cardiac death during pregnancy
    Pregnant women who develop hemodynamically unstable ventricular tachycardia or ventricular fibrillation need cardioversion or defibrillation. In patients with an extended interval (2-T, in whom symptoms of the disease were previously noted, prolongation of therapy with β-adrenoreceptor blockers is necessary throughout the entire period of pregnancy and after childbirth, with the exception of
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