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Treatment of depression

The leading treatment for depression today is psychopharmacotherapy. Along with medications, methods of physical, phyto, and psychotherapy with elements of psychocorrection and other socio-rehabilitation methods are widely used. Psychotherapy, carried out in a complex with medicinal treatment (mainly aimed at correcting a depressive distortion of thinking, reducing aggression, hopelessness) is most effective.

Since the beginning of the era of psychopharmacology, antidepressants (timoanaleptics) have been the main place among the therapeutic effects of depression. In addition to these, drugs of other groups are widely used:

Antipsychotics (neuroleptics). They have the following properties: they reduce psychomotor activity, relieve psychomotor arousal, and provide antipsychotic action.

Anxiolytics (tranquilizers). They stop anxiety, emotional tension, fear, sleep disturbances.

Nootropics These are drugs that positively affect the metabolic processes of the brain, increase the resistance of brain structures to various adverse factors, in particular to hypoxia and extreme loads.

Psychostimulants. They increase mental and physical performance, endurance, reduce the feeling of fatigue.

Mood stabilizers. This is a group of drugs that regulate affective manifestations.

They are mainly used at the stages of preventive treatment, as a rule, in specialized psychiatric institutions.


In the treatment of depression, the use of auxiliary agents such as physio and phytotherapy gives a good effect. When irritability, sleep disturbance, herbs with a sedative component are used (valerian, motherwort, hawthorn, peony, oregano).

Phytoantidepressants are separated into a separate group. These include Leuzeu, Aralia, Zamanihu, etc. Among these funds, it is necessary to highlight the extract of the herb St. John's wort.

The active substances included in its composition made it possible to create a modern drug, the gelarium and the new passit. Herbal preparations are well tolerated, free from side effects, can be combined with other drugs and do not show signs of dependence.

A special role in the elimination of depressive manifestations belongs psychotherapeutic effects.

A study of the action of iproniazid has shown that it inhibits the enzyme monoamine oxidase (MAO). This enzyme deactivates norepinephrine, dopamine, serotonin (substances-neurotransmitters produced by the structures of the nervous system and promote the transmission of nerve impulses). It is these substances that play an important role in the activity of the central nervous system, and their imbalance causes a number of somatic and psitogenic disorders, one of which is depression. In depressions, a decrease in the activity of the transmission of impulses in the neuromagative systems is observed.
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Treatment of depression

  1. Depression
    Depression is a mental disorder, the main features of which are: a decrease in mood (hypothymia), a negative, pessimistic assessment of oneself, one’s position in the surrounding reality, one’s future. Along with this, depression is often accompanied by inhibition, a decrease in the motivations for activity, dysfunctions in the work of many organs and systems.
  2. Depression
    Depression is a mood disorder characterized by sadness and pessimism. The causes of depression are unknown, but the basis of its pharmacotherapy is the hypothesis that the manifestations of the disease are due to a deficiency of dopamine, norepinephrine and serotonin in the brain or dysfunction of the receptors of these mediators. With major depression, the level of cortisol in the blood is increased by 50% and its circadian rhythm is disturbed.
  3. 8.1. ALARM AND DEPRESSION
    Among all psychopathological syndromes encountered in somatic practice, anxiety and depression are the most common. These disorders are usually considered in a single continuum. Anxiety and depression are often combined with somatic disorders (comorbid conditions), make them more severe, prognosis. Timely treatment of them significantly optimizes internal therapy.
  4. Depression
    Depression is a condition characterized by a triad of symptoms: depressed, depressed, melancholy or anxious mood, decreased mental activity and decreased motor activity. The term depression comes from the Latin word deprimo, meaning "to oppress." This triad constitutes the core of the clinical picture. Accompanied by depression can be a variety of clinical
  5. Depression
    Physical blocking This description applies to those who have PSYCHOTICAL DEPRESSION. Those who suffer from temporary emotional depression caused by adverse life circumstances or some unpleasant event, it is better to refer to the articles AGORAHOBIA, ALARM or ANXIETY. The main symptoms of depression are: loss of interest in daily activities, feeling
  6. Depression
    The manifestations of depression are very diverse and vary depending on the form of the disease. The most typical symptoms of this disorder are listed below. The most typical manifestations of depression Emotional manifestations • Sadness, suffering, depressed, depressed mood, despair. • Anxiety, feeling of internal tension, waiting for trouble. • Irritability. • Guilt feelings, ideas of self-blame. •
  7. Depression
    Cause The most common cause of depression is mental stress. Also, depression is possible due to overwork, brain injury (possibly in the past), prolonged and severe disease of internal organs, surgery, prolonged pain, poor blood supply to the brain, congenital mental impairment of the integrity of the personality. Symptoms Depressed, joyless
  8. Depression Scale
    The questionnaire was developed for the differential diagnosis of depressive states and conditions close to depression, for screening diagnostics in mass studies and for the purpose of preliminary, pre-medical diagnostics. Test adapted by T.I. Balashova. Full testing with processing takes 20-30 minutes. The subject marks the answers on the form. Depression level (UD) is calculated using the formula: UD
  9. Depression
    Depressive syndrome - a combination of melancholy mood with a decrease in mental and physical activity. Assessment of the severity of depression is within the competence of the psychiatrist, since its external signs do not always reflect the severity of the condition and the risk of possible suicide. Suicidal attempts, refusal to eat, anxious motor excitation of the patient require urgent hospitalization in
  10. Depression in patients with myocardial infarction
    In recent decades, it has been established that depressive and anxiety disorders increase the risk of developing MI (Todaro JF et al., 2003). In a multicenter randomized study GISSI-2, it was found that 40% of patients in the preceding 3 months before the development of MI experienced a depressed mood. Other researchers report that depression develops as a result and complication of MI (Honig A. et.
  11. Depression of the ST segment as a manifestation of vegetative dystonia
    Other changes in the ECG caused by impaired autonomic nervous system tone should include depression of the ST segment, which is noted in hypersympathicotonia. In the differential diagnosis takes into account the characteristic clinical picture; depression of the ST segment, revealed in young people, especially women, often with concomitant tachycardia, without typical angina pectoris manifestations. This
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