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Systemic lupus erythematosus

There are acute and chronic forms of lupus erythematosus.

The acute form is characterized by pale red and red edematous rashes, often on the face, which merge into spots. Rashes can be found on the body, buttocks, limbs, often on the hands and fingers, less often on the mucous membranes. They resemble seborrheic eczema or exudative erythema. Sometimes foci are combined with bubbles and crusts. The course is severe with high fever, septic phenomena, general weakness, pain in the joints and muscles.

The chronic form begins with the appearance of pink-red spots, covered with gray scales, which are removed with great difficulty. In the area of ​​the lesion, the skin is thinned, atrophied. The main symptoms of lupus erythematosus include hyperemia, hyperekeratosis and atrophy. Neuralgia, polyradiculoneralgia, epileptiform seizures, and autonomic and neurological reactions are often added to this.
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Systemic lupus erythematosus

  1. SYSTEM RED LADY
    Systemic lupus erythematosus (SLE) is a systemic autoimmune disease of unknown etiology based on a genetically determined disorder of immunoregulatory mechanisms that determines the formation of a wide spectrum of organ-specific autoantibodies to various components of the nucleus and the formation of immune complexes that cause the development of immune inflammation in the tissues of various organs.
  2. Systemic lupus erythematosus
    Systemic lupus erythematosus (SLE) is an acute or chronically occurring systemic disease with severe autoimmunization characterized by a predominant lesion of the skin, blood vessels, and kidneys. • Mostly young women get sick. • Insolation and taking certain medications are often provoking factors. • The processes of autoimmunization are accompanied by the appearance of antinuclear autoantibodies to
  3. Systemic lupus erythematosus
    Systemic lupus erythematosus is a chronic polysyndromic disease of the connective tissue and blood vessels, developing in connection with the genetically determined imperfection of immunoregulatory processes. Etiology. The significance of viral infection against the background of genetically determined immunity disorders is assumed. Pathogenesis: circulating antibodies are formed, of which important diagnostic and
  4. Systemic lupus erythematosus.
    Systemic lupus erythematosus is a disease of the autoimmune nature. With the development of the disease by the patient's body, antibodies are produced to the nuclear substances of their own cells. Mostly sick girls - teenagers. Fever can be constant for weeks and months. Its reason is long incomprehensible. Rash. "Lupus butterfly" - a group of small and medium in size
  5. SYSTEM RED LADY
    - chronic systemic autoimmune disease of the connective tissue and blood vessels, characterized by severe course, steady progression and polymorphism of clinical manifestations. Main clinical manifestations The most common clinical sign of systemic lupus erythematosus is joint damage in the form of marked migrating polyarthralgia or arthritis. Joint deformity
  6. SYSTEM RED LADY
    Systemic lupus erythematosus (SLE): a nonspecific autoimmune disease of the body, which is accompanied by lesions caused by cytotoxic antibodies and the deposition of immune complexes. SLE is observed in many species of mammals (man, mouse, monkey, cat, dog and horse). As a rule, the disease occurs in a subacute or - more often - in a chronic form, accompanied by
  7. Systemic lupus erythematosus
    Systemic lupus erythematosus (SLE) is a chronic polysyndromic disease, predominantly in females, developing against the background of genetically determined imperfections of immunoregulatory processes, leading to uncontrolled production of antibodies to its own cells and their components with the development of autoimmune and immunocomplex inflammation. EPIDEMIOLOGY. Accurate data about
  8. Systemic lupus erythematosus (code? 32)
    Definition Systemic lupus erythematosus is a disease that develops on the basis of a genetically determined imperfection of immunoregulatory processes, leading to the formation of antibodies to its own cells and their components, the emergence of immunocomplex inflammation that affects many organs and systems (MM Ivanova). Statistics. Sickness is very variable, varies in different regions
  9. 3.3. SYSTEM RED LADY
    NSAIDs are prescribed to relieve constitutional and musculoskeletal manifestations of SLE, as well as moderately severe serositis. Recommended: diclofenac (tab. 25 mg) at 75-150 mg / day, ketoprofen (cap. 50 mg, tab. Forte 100 mg) at 100-300 mg / day, lornoxicam (tab. 4 and 8 mg) according to 8-16 mg / day., Meloxicam (tab. 7.5 and 15 mg) at 7.5-15 mg / day., Celecoxib (cape. 100 and 200 mg) 200-400 mg / day.,
  10. Systemic lupus erythematosus
    -cutaneous cm: butterfly, erythema of the periungual, periarticular, other localization, capillaries, polymorphic rashes, cheilitis, enanthema, dystrophy of the skin, hair - articular sm: polyarthritis, polyarthralgia - muscular sm: myositis, myalgia –s- m Rayno-pulmonary sm: pneumonitis, pleurisy, pneumosclerosis - renal sm: nephritis - cardiac sm: myocarditis, endocarditis, pericarditis, myocardial dystrophy,
  11. 80.DIFFUSE DISEASES OF THE CONNECTIVE TISSUE. CLASSIFICATION. ETIOLOGY, PATHOGENESIS. SYSTEM RED LADY. CLINIC, DIAGNOSTICS, TREATMENT PRINCIPLES.
    Diffuse diseases of comp. Tk (DBST) - a group of nosological forms, systemic autoimmune and immuno-complex inflammation or excessive fibrosis education (with systemic scleroderma) , mixed connective tissue disease and rheumatic polymyalgia. Etiology - can
  12. Pathology of the immune system. Hypersensitivity Reactions. Autoimmunization and autoimmune diseases. Amyloidosis. Systemic lupus erythematosus. Scleroderma. Immune Deficiency Syndrome (AIDS).
    1. Forms of immunity 1. focal 3. specific 2. diffuse 4. nonspecific 2. Mechanical protection is provided by 1. skin 4. peripheral nerves 2. blood 5. vascular mucosa 3. vascular endothelium 3. Humoral nonspecific components of the immune response 1. sweat 4. mesangiocytes 2. macrophages 5. lacrimal fluid 3. neutrophils 4. To establish compliance: ORGANIZING RESPONSIBLE
  13. Neonatal lupus erythematosus
    DEFINITION Newborns from mothers with systemic lupus erythematosus and other diffuse connective tissue diseases may have transient dermal lupus, heart rhythm disturbances (congenital heart block) and hematological disorders (thrombocytopenia, leukopenia, hemolytic anemia), as well as immunological signs of systemic lupus erythematosus what is called
  14. lupus erythematosus
    Lupus erythematosus - collagenosis, an important role in the pathogenesis of which is a violation of the regulatory function of T-lymphocytes, the appearance of immune complexes and their deposition in the tissues. Mostly women are ill (about 90%) at the age of 20-45 years. The causes of the disease are unknown. It is assumed that provoking factors (some chemicals, drugs, infection) in combination with
  15. lupus erythematosus
    Lupus erythematosus is a group of connective tissue diseases that have autoimmune pathogenesis and affect predominantly exposed skin and internal organs. Etiology and pathogenesis. Hereditary predisposition and, apparently, viral infection, which contribute to the development of autoimmune processes, have a leading role in the etiology of lupus erythematosus. Clinic. Allot
  16. RED LADY (LUPUS ERYTHEMATODES)
    Etiopathogenesis. Dermatosis is etiologic. Theories of the origin of lupus erythematosus: 1. Autoimmune theory - it plays the main role. In the serum of patients with lupus erythematosus detect a high level? - globulins, among which an unusual protein - macroglobulin, the so-called anti-nuclear factor, damaging the nucleus of cells, especially leukocytes. In peripheral blood and
  17. SYSGEM RED LADY
    In accordance with modern concepts, systemic lupus erythematosus (SLE) is a chronic relapsing polysyndromic disease of predominantly young women and girls, developing against the background of the genetically determined imperfection of immunoregulatory processes, leading to uncontrolled production of antibodies to its own cells and their components, with the development
  18. lupus erythematosus
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  19. Chronic lupus erythematosus
    chronic polysyndromic disease of the connective tissue and blood vessels, developing due to the genetically determined imperfection of immunoregulatory processes. Etiology. The significance of viral infection against the background of genetically determined immunity disorders is assumed. Pathogenesis: the formation of circulating autoantibodies, of which the most important diagnostic and pathogenetic significance
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