home
about the project
Medical news
For authors
Licensed books on medicine
<< Previous Next >>

CHRONOLOGICAL ASPECTS OF EARLY DIAGNOSTICS OF NEFROBLASTOMAS

Begun I.V., Tarasevich R.A., Gorovikova M.M.

Republican Scientific and Practical Center of Pediatric Oncology and Hematology,

Republic of Belarus

Research objective: Analysis of cases of detection of nephroblastoma in infants in the early stages.

Patients and methods: The data of ultrasound imaging were summarized in 14 term-born infants of both sexes under the age of one year (median - 7.7 months) with morphologically established nephroblastoma in stages 1-2 of the disease. All children were in a group of 20 patients with malignant tumors of the kidneys who were admitted for examination and treatment at the RNCPDOG from 1999 to 2009.

Results: In the vast majority of patients, there was no anamnestic evidence of suspected kidney tumor during the last prenatal ultrasound diagnosis performed at 32-38 weeks of gestation. In this regard, in the course of the study, the hypothesis of a “perinatal visualization time point” of reference for tumor growth was put forward. In 100% of cases, the method of effective primary postnatal imaging of the tumor in the outpatient network was ultrasound (ultrasound). The terms of tumor diagnosis from birth were between the third and eleventh months of life (231 (185-303) days).
The minimum tumor size was 4 cm, the maximum - 14 cm with an average volume of 283 (186-350) cm3. There was no correlation between the age of patients and tumor volume. The number of doubling the tumor from the estimated minimum visualized volume (1 cm3) to the diagnosed volume was 8.02 (7.45-8.37). The averaged values ​​of the periodics of doubling the tumor were obtained - their full range was 13-44 days, which does not contradict the single observations described in the specialized literature. A quantitative analysis of the growth retardation of the neoplasm characteristic of the clinical phase of its development at this stage of the study was not conducted.

Conclusions: Ultrasound is the most effective method for primary imaging of a kidney tumor in an infant. Nevertheless, the diagnosis of kidney neoplasm even in the early stages is made when the tumor volume is significantly higher than the minimum diagnosed volume. The study attempted to illuminate the quantitative aspects of the growth of the most common kidney tumor in children - nephroblastoma. A possible perinatal “visualization point” of the tumor growth reference is indicated.
<< Previous Next >>
= Skip to textbook content =

CHRONOLOGICAL ASPECTS OF EARLY DIAGNOSTICS OF NEFROBLASTOMAS

  1. Psychological aspects of the meaning of life in early adolescence
    I found that the most interesting person among my friends is myself. (S. Kierkegaard) Many psychologists define the period of early youth as important, unique, but at the same time difficult, critical, and conflict. A developing personality suddenly discovers that within it there is a whole new world of experiences that lives by its own laws, a world frightening and alluring at the same time.
  2. WAYS TO IMPROVE EARLY DIAGNOSTICS OF MALIGNANT NON-EDUCATIONS
    M.V. Kazantseva State Clinical Oncology Center No. 1, Krasnodar Concern and increased attention to oncological problems are one of the characteristic features of public health in all developed countries. This is due, first of all, to the steady growth trend in cancer incidence, which has reached quite high rates and will increase in the foreseeable future.
  3. PCR-MMK - a method for the early diagnosis of cancer cells
    From the first cancer cell due to its division, a nodule 1-2 mm in diameter is first formed in the tissue. But already from this size, cancer cells induce angiogenesis and lymphangiogenesis within the nodule. With the beginning of the outflow of blood and lymph from the nodule, the cancer cells are separated from it and spread with blood and lymph throughout the patient's body - the cancer becomes a disease of the whole organism of the patient. From this
  4. QUESTIONS OF EARLY DIAGNOSTICS AND SCREENING OF MALIGNANT TUMORS
    QUESTIONS OF EARLY DIAGNOSIS AND SCREENING OF MALIGNANT
  5. Methods for the early diagnosis of cancer cells
    Methods for the early diagnosis of cancer
  6. EVALUATION OF THE RESULTS OF THE SCREENING PROGRAM ON EARLY DIAGNOSIS OF BREAST CANCER IN THE KHANTY-MANSIYSK AUTONOMOUS DISTRICT - UGRA
    ON THE. Zakharova 1, SW. Duffy2, J. Mackay3, E.V. Kotlyarov4 1Cancer Research UK, Center for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom, 3Research Department of Genetics, Evolution
  7. Biochip or microarray - a device for the early diagnosis of cancer cells, tracking cancer treatment and monitoring cure
    A biochip is an organized placement of DNA or protein molecules on a special carrier - the “platform”. The platform is a plate with an area of ​​only 1 cm2 or a little more. It is made of glass or plastic, or of silicon. A lot of DNA or protein molecules can be placed on it in a strictly defined order. Hence the presence of the word “micro” in the term. On a biochip, you can
  8. Cell Proteomes - Importance for Medicine, Early Cancer Cell Diagnosis and Cancer Treatment
    Soon, current medicine will be a thing of the past. P. Ehrlich’s long-standing dream - to have medicine without harming the patient - the “magic bullet”, will become a reality. It will destroy: in infections - pathogens, in cancer - cancer stem cell, without damaging healthy cells, acting on the protein that causes the disease. For each patient, individual medicines will be created. It started after
  9. Chronological, biological, social and psychological ages and possible options for their relationship
    When these levels and their correlation are identified, the chronological age — the number of years a person has lived since the birth of years and months — means little to understand the state of his body, his personality traits, his qualities as a subject of activity. It is much more informative to obtain a correct judgment about all of his hypostasis is his biological, social and
  10. 44. QUESTION, INSPECTION, PALPATION IN DISEASES OF THE BLOOD SYSTEM. RESEARCH OF SPLEEN, DIAGNOSTIC VALUE. PRINCIPLES OF EARLY DIAGNOSIS OF BLOOD DISEASES.
    Questioning: complaints of weakness, light fatigue, dizziness, shortness of breath during physical exertion, palpitations in case of anemia, leukemia, myeloid hypoplasia. Many diseases of the blood system are accompanied by fever, fever, loss of appetite and weight loss. With B12 anemia, a burning tip of the tongue and its edges is characteristic. With Fe anemia, a perversion of taste (the use of chalk,
  11. MODERN ASPECTS OF DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION
    Pulmonary hypertension (LH) is a pathological syndrome caused by an increase in blood pressure in the pulmonary circulation (MCC). The pressure in the ICC is considered increased if it exceeds normal values: systolic - 26-30 mm Hg, diastolic 13-19 mm Hg. LH causes severe disturbances in vital organs and systems, especially in the lungs and heart. It causes
  12. The main aspects of the diagnosis of infertility of a married couple
    The main aspects of the diagnosis of infertility
  13. Abstract. The main aspects of the diagnosis of the causes of infertility of a married couple, 2009

Medical portal "MedguideBook" © 2014-2019
info@medicine-guidebook.com