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Pathological physiology

PATHOLOGICAL PHYSIOLOGY

A.V. Pasechnik, E.G. Moiseeva, V.A. Frolov, G.A. Drozdova Inflammation and metabolic disorders 2011
Treatment of inflammatory periodontal diseases reduces the levels of such factors of cardiovascular risk, as C-reactive protein and fibrinogen, established by American scientists. This is another proof of the connection between periodontal diseases and cardiovascular pathology. C-reactive protein (CRP) and fibrinogen are acute-phase proteins and systemic markers of inflammation.

As it was stated at the 82nd general session of the International Association of Dental Research (Honolulu, Hawaii, USA), complex treatment resulted in a significant decrease in initially elevated concentrations of CRP (not less than 3 mg / L) and fibrinogen (not less than 3 g / l). The concentration of CRP and fibrinogen decreased by 9 months with mechanical treatment only, and by 6 months with the addition of an antibacterial drug (p <0.05).

Thus, in patients with elevated levels of CRP, the removal of plaque bacteria in combination with local antibiotic therapy reduced the concentration of CRP to the characteristic of low cardiovascular risk figures.

Today, we and many other authors develop effects of complex therapy on the levels of other markers of inflammation - cytokines, including effects on metabolic proaterogenic parameters.

For students, clinical residents and post-graduate students of the medical faculty, studying in the specialties "Stomatology", "Medical business"
Toolkit Hypoxia 2010
Definition of the concept, types of hypoxia. Etiology and pathogenesis of various types of hypoxia. Compensatory-adaptive reactions. Violations of basic physiological functions and metabolism. Mechanisms of hypoxic necrobiosis. Discrimination. Adaptation to hypoxia and disadaptation
Toolkit Pathological physiology of the endocrine system 2010
General characteristics of the endocrine system. The main manifestations of endocrine disruption. The main etiological factors and pathogenetic mechanisms of development of endocrine pathology. Violation of the central mechanisms of regulation of endocrine functions (central level of damage). Ways of central regulation of autonomic functions. Pathological processes in the gland itself. Peripheral (extra-iron) mechanisms of disturbance of activity of hormones. Intrauterine endocrinopathies. Compensatory-adaptive mechanisms. The role of endocrine disorders in the pathogenesis of nonendocrine diseases. Principles of treatment and prevention of endocrine disorders.
Leonova EV Chanturia A. V. Wismont F. I. Pathological physiology of the blood system 2009
Blood is an extremely complex, especially vital system, which largely determines the integrity of the body. For a doctor of any specialty, you need to know the basics of hematology. Pathophysiological aspects of blood system disorders for the clinician are of significant importance. This is the subject of this manual. It includes modern information on hematopoiesis, violation of erythro-, leuko-, thrombocytopoiesis, pathology of hemostasis, anti-hemostasis, typical forms and reactive changes in erythrocyte, leukocyte, platelet, hemostasis and anti-hemostasis systems, as well as issues related to etiology, pathogenesis, changes blood in the most common types of anemia, erythrocytosis, leukemia, hemostasiopathy.

The expediency of the publication of this manual is due to the rapid development of hematology, its enrichment with new achievements and ideas that have not been adequately reflected in the educational literature, the need to present them in an accessible form for students.

The purpose of the classes is to study the causes and mechanisms of disturbances in the processes of erythro-, leuko-, thrombocytopoiesis, hemostasis-antigemostasis; typical changes in blood elements, etiology, pathogenesis of various types of anemia, erythrocytosis, leukemia, hemostasiopathy; changes in their blood picture.

The objectives of the classes are: ...
Toolkit Pathology of external respiration 2009
Regulation of respiration. Violation of the functions of the respiratory center. Forms of violation of the DC. Typical violations of gas exchange function of the lungs. Violation of alveolar ventilation. Types of hypoventilation disorders. Violations of ventilation-perfusion relations. Diffusion of the lungs. Pathological types of respiration. Terminal types of respiration. Dissociated breathing. Dyspnea. Etiology, pathogenesis, consequences of cough. Insufficiency of external respiration.
Yu.I. Kosyuga, V.A. Lyalyaev, ON Shevantayeva Fever and hyperthermia 2009
Methodical instructions for independent work of students of the Faculty of VSO (correspondence form of training)

Fever and hyperthermia. Etiology of fever. Pathogenesis of fever. Stages of fever. Classification of fever. The value of temperature curves for fever. Changes in organs and systems with fever. Meaning of a fever. Hyperthermia. Classification. Differences from fever. Endogenous hyperthermia. Exogenous hyperthermia. Questions for self-monitoring of knowledge on the topic "Fever and hyperthermia"
Tutorial Kidney pathophysiology 2008
The "Teaching aid" presents in detail the theoretical information block, which contains a fundamental material on the pathophysiology of the kidneys, as well as test tasks with reference replies to them and situational tasks. Materials are intended for students of medical institutes and universities of medical and biological profile, can be useful to residents, graduate students, subordinates and nephrologists, including for self-monitoring.
Tutorial Typical pathological processes. Pathophysiology of metabolism. 2008
The manual contains educational and methodological material on the most important section - the pathophysiology of metabolism of the curriculum of the discipline "Pathophysiology." In the process of education, students face the need to integrate knowledge gained in the study of metabolism in the disciplines of biochemistry, physiology, pathological anatomy, pathophysiology, and development of skills in applied clinical thinking. The task of this training manual is to teach the student the clinico-pathophysiological understanding of the knowledge obtained in the study of this section of pathology for subsequent use in clinical disciplines. In the process of independent work, students get an opportunity to get acquainted with the generalized material of textbooks, in-depth information from additional sources. To facilitate the development of this knowledge, algorithms of the causes, mechanisms and manifestations of metabolic disorders in the form of tables and charts are given. On an example of test tasks it is possible to analyze and fix the received information. Situational problems allow to develop clinico-pathophysiological thinking and skills of differential diagnostics. The manual is intended for students of medical schools, it can be useful for interns, clinical residents, graduate students and practicing doctors.
Toolkit Pathology of the mouth 2007
Pathology of the oral cavity. General characteristics. Inflammatory diseases of the oral mucosa. Diseases of the oral cavity. Diseases of the teeth. Inflammatory diseases of maxillofacial apparatus. Features of their origin and flow. The role of local hypoxia in the pathogenesis of inflammatory and dystrophic lesions of the tissues of the maxillofacial region. Malformations of the maxillofacial apparatus. The role of genetic factors in their development. Tumors of the oral cavity. Pathology of the mouth and indigestion. Disturbance of digestion in the oral cavity. The role of disorders of the dentoalveolar apparatus in disorders of the gastrointestinal tract. The role of chronic inflammatory processes of the oral cavity in the formation of pathological immune reactivity. The main manifestations of the pathology of the blood in the oral cavity. The main manifestations in the oral cavity of chronic cardiovascular insufficiency. The main manifestations in the oral cavity of the pathology of the liver and gastrointestinal tract. The main manifestations in the oral cavity of the pathology of the kidneys, the insular apparatus. The relationship between external respiration disorders and the pathology of oral tissues. The main manifestations in the oral cavity of violations of phosphorus-calcium metabolism. The role of hormonal disorders in the formation of the pathology of the dentoalveolar apparatus, their manifestations in the oral cavity. The main manifestations in the oral cavity of chronic intoxication with heavy metals.
Toolkit Bank of situational tasks 2007
State Educational Institution of Higher Professional Education "Krasnoyarsk State Medical Academy of the Federal Agency for Public Health and Social Development" (State Educational Institution of Higher Professional Education). Faculty of curative medicine. 3 course.
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