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Sjogren's disease

• More common in middle-aged and older women.

• Characteristic:

a. Dry Syndrome:

° xerostomia (dry mouth);

° xerophthalmia (dry eyes), keratoconjunctivitis.

b. Bilateral enlargement of the parotid salivary glands due to diffuse infiltration by lymphoid and plasma cells, which partially or completely replace the gland tissue.

in. Changes resembling rheumatoid arthritis or other rheumatic diseases (systemic lupus erythematosus, scleroderma, etc.).

• In the blood, pronounced polyclonal hypergammaglobulinemia.

• Malignant lymphomas often develop.
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Sjogren's disease

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