the main
about the project
Medicine news
To the authors
Licensed books on medicine
<< Ahead Next >>

Auxiliary drug support.


I left this topic in the end, because any medications are only an aid in the holy work of improving the figure. Rely on them completely and completely impossible. When advertising promises that the drug will do everything for you without restrictions in food and physical activity, and even without damage to health - do not believe it!
Farm drugs that help get rid of the hated kilograms are then scolded, then extolled. Neither is fair. Despite serious side effects, many of these drugs have helped in the treatment of severe degrees of obesity that are life-threatening.
I often notice that many of my patients are very wary of all my prescribed drugs and biologically active supplements. At the same time, almost all of them are forced to take various strong medicines due to such effects of obesity as increased A / D or diabetes. Many are very wary of only the name itself - dietary supplements.
I will repeat it again and I want you to remember it - there is no medicine for obesity!
Not a single drug in itself is capable of affecting the metabolism so that it would permanently save you from the hated excess fat.
At the same time, I argue that it is impossible to reduce the amount of food consumed while maintaining the nutritional value of the diet without the active use of biological active additives. But in order to navigate in their diversity, you need at least to imagine the mechanism of their actions and the goals that we achieve by introducing them into your diet. All these drugs perform a specific task at certain stages of the procedure. I want to tell you about some of them that I use most often.
The action of these drugs - makes the method easily tolerated and not painful, “wean” from sweets, moderate appetite, save from evening and nightly gluttony, improve the body's energy:
1. Due to its vital role in the metabolic process, the liver is particularly susceptible to the harmful effects of various toxic components. It is especially important to support the liver during weight loss, as with the rapid decrease in fat mass, an additional amount of toxic metabolites enter the blood. Requires intensive work of this body for the removal of degradation products of fat. In general, with any method of losing weight, this body is under tremendous pressure. The liver is the largest and one of the most complex human organs, the first line of defense, a key part of the detoxification system, a powerful filter that cleans the blood from harmful substances. Every minute, the liver filters about a liter of blood! To preserve the health of the body is vital to maintain the safety of liver cells. In this regard, it is necessary to take measures from the very first days to prepare and protect this body. It should be possible, even before the procedure, to start a course of taking drugs - hepatoprotectors, such as, for example, Liver Pro from Santegra®, which protect the liver cells. It is simply vital for those patients who have chronic liver disease or had viral hepatitis in their time. For people whose age is approaching 40, this is also a prerequisite.
2. The next stage of purification of the body is aimed at combating changes caused by the natural aging process, stress, and life turmoil. Irrational food, bad habits, lack of sleep worsen our health. At this stage, it is advisable to use - Red Clover Forte (a product of Santegra®) to collect medicinal herbs, helping to further cleanse the body, eliminate toxins from the blood and cells. This drug also completes the stages of cleaning the liver, helps to normalize its work. Improves the bowels, metabolic processes, strengthens the immune system. The active substances that are part of Red Clover Forte contribute to further detoxification of the body by increasing the barrier function of the liver, laxative, choleretic, diuretic action. Possess antioxidant, antibacterial and anti-inflammatory properties.
3. Sugar has always been necessary for man to survive. The brain eats only sugar in the form of glucose; the whole body prefers sugar as an energy source. Even small children prefer sweet taste to anybody else. Why is a person sometimes so uncontrollably drawn for sweets? It has long been observed that abnormal sweets are peculiar to some people. This has a figurative name - carbohydrate thirst. Sugar is needed by the body. But sometimes not in such quantities as we use it. There is one simple rule. If you constantly want something, it means that your body lacks this. In order to understand this, I will try to briefly describe how sugar (glucose) is transformed in our body. There are two ways to break down glucose (sugar): glycolysis and the pentose phosphate pathway. For ease of understanding, I can only say that if glycolysis plays an important role in energy metabolism, then the pentose phosphate pathway eventually leads to the formation of fats. And as it turned out, this is due to the lack of a number of trace elements in the body, and above all - chromium. The lack of this particular element often causes a shift in the carbohydrate metabolism process specifically for the pentose phosphate cycle. At the same time, a person is forced to consume more sweets, the nervous system still receives less sugars, and most of them are processed and deposited in fats. But it is worthwhile for such patients to add chromium preparations to the diet, as he literally in front of his eyes forgets about the “sweet life”. Since the concentration of chromium in most types of foods is too low to affect the concentration of sugar in the blood, many nutritionists recommend that their patients supplement the diet with chromium supplements. The positive effect of chromium on insulin sensitivity plays a key role in the treatment of depressive states accompanied by a pathological burden to the use of carbohydrates. Chromium supplementation has a positive effect on pathological disorders of appetite, decreases cravings for carbohydrates, and libido normalizes. Chromium supplements are usually well tolerated and do not cause side effects. I recommend my patients suffering from pathological carbohydrates or having a history of diabetes to take chromium preparations. One of the latest developments in this area is the product of Santegra® company - Reglucol ™, in which the key ingredient of the formula is bioactive chromium (in the form of the natural complex Chromium + GPM ™). This is a natural form of chromium with high bioavailability. In the production of Chromium + GPM ™, a multistep fermentation process is used, as a result of which chromium, yeast (sacchromyces cervisiae) and probiotics (bifidobacterium bifidum and lactobacillus acidophilus) form glycoprotein matrices. In this process, chromium from an inorganic form is converted into an organic, chelated form, which greatly increases the bioavailability of this important trace element.
4. Calcium is the most common mineral in the human body. It not only plays an important role in the formation of inert tissue, but also forms part of the blood, cellular and tissue fluids. This trace element directly affects the processes of muscle contraction and, therefore, depends on it all the physical activity of a person. It also affects the stimulation of the functions of a number of enzymes and hormones involved in the regulation of lipid metabolism. Its role is in the metabolic transformation of fats. Its high content in the body accelerates their "digestion" of cells and prevents them from accumulating in adipose tissue. It turned out that an increased amount of calcium suppresses calcitriol production, which makes any diet more effective. It is known that a decrease in calcitriol production increases the intensity of fat utilization and reduces the level of lipogenesis. Although calcium is found in many foods, providing them with an organism is not an easy task, as it is one of the hard-to-digestible elements. For example, even an excess of saturated fat prevents calcium absorption in the intestine. Scientists at Harvard University studied 45,000 patients and proved that there is no connection between calcium-rich food and kidney stones. And even the opposite - natural calcium-rich food reduces the risk of stone formation. But calcium, which is included in vitamin complexes and nutritional supplements, unfortunately does not possess this property. And only recently a new calcium-containing product, Camosten ™, a Santegra® product, was created that is easily soluble in water and quickly absorbed by the body. Calcium citrate, part of Camosten ™ is one of the most bioavailable forms of calcium. It was established that the use of calcium citrate does not lead to a violation of biochemical blood parameters and does not cause kidney stone formation. The advantage of this Santegra® product is that it does not contain sugar, which makes it possible to recommend it for diabetics and anyone who adheres to the principles of healthy eating and limits the daily use of sugar. This drug also includes magnesium, which works closely with calcium, activating more than 300 enzymes in the human body. It is important to remember that the lack of magnesium in the diet rich in calcium causes calcium retention in all tissues, which leads to their calcification. Sufficient intake of magnesium in the body is simply necessary for the full absorption of calcium, phosphorus, sodium ascorbic acid and vitamins of group B.
5. Vitamins. By themselves, vitamins do not create anything. They are not “building blocks” in cell architecture. But to live without them is impossible. Vitamins catalyze key metabolic reactions, without vitamins, these processes are greatly inhibited. In the absence or lack of these substances, dangerous changes occur in the body, the severity of which directly depends on the degree of vitamin deficiency. The technology of obtaining vitamins and multivitamin products is reliably worked out and guarantees both high purity and good preservation, moreover, it is strictly controlled. Currently, US law requires mandatory certification of GMP production only from manufacturers of pharmaceutical (medicinal) drugs. The certification of dietary supplements according to the GMP standard in the USA is currently carried out on a strictly voluntary basis. There are fewer than ten out of nearly a thousand such manufactures of dietary supplements with a similarly high level of certification. A typical representative of such a company that produces expensive but highly purified and most effective vitamin-mineral complexes is SANTEGRA, which manufactures its products at one of the largest US enterprises, GARDEN STAYE NUTRITIONALS. Its vitamin complex, Ultivit, showed quite good clinical results. What vitamin complex to choose - decide for yourself. It depends largely on the individual perception and portability of the components included in each of them, financial capabilities and the availability of their acquisition.
I believe that the intake of any vitamin-mineral complexes is a tough and necessary condition for creating a balanced diet.
6. Along with vitamins, the need for which, of course, has been established, substances that take a special place in the classification and can be called vitamin-like compounds or bioflavonoids participate in lipid metabolism. You must have heard this buzzword. The most important among them in the normalization of lipid metabolism and the treatment of obesity is carnitine. Now, perhaps, you will not find a single bioadditive from the category of so-called "fat burners", which would not include L-Carnitine. The properties that he is credited with are fantastic. I am often asked to comment on this “miracle supplement,” its effect on fat burning. I have to say, L-Carnitine has nothing to do with the "burning" of fat! Fats burn only in the mitochondria of muscle cells when performing strictly defined physical activity! It is important to understand and remember! Mitochondria is a personal powerhouse of the cell, one of the end points of the metabolism. The faster the fuel is supplied to the mitochondria, the faster the metabolism occurs. No pills and drugs capable of burning fat! Any drugs and substances can only have a supporting role at different stages of the most complicated process of normalizing lipid metabolism and treating obesity. A unique feature of carnitine is that it increases the permeability of cell membranes for fatty acids. While not increasing the rate of breakdown of adipose tissue, it increases the absorption of fat by the body for energy purposes, helps the fats from the blood through the cell membranes to penetrate the muscle cells, where they successfully burn with energy release. Only such is the mechanism of consumption of adipose tissue! A remarkable property of carnitine is its ability to reduce cholesterol levels in the body and slow down the formation of vascular atherosclerotic plaques. Under his influence, the formation of lecithin in the liver is enhanced, and since lecithin “washes out” cholesterol from atherosclerotic plaques, it can be said that carnitine is one of the few compounds that can be used to achieve active longevity. In addition, L-carnitine contributes to the detoxification of the liver, the synthesis of protein and glycogen, more active splitting of lactic and pyruvic acids, which are "fatigue toxins." It is more expedient to take carnitine half an hour before any aerobic exercise. In this case, the fats, entering the muscle cells, burn there most efficiently.
7. Coenzymes are cofactors on which the work of relatively large and complex enzymes depends. One of the most famous coenzymes is Q10 (ubiquinone). According to the molecular structure, it is similar to vitamin K. Now many unique properties are attributed to this substance, and perhaps that is why it is part of almost all elite cosmetics. Coenzyme Q10 is a necessary component for at least three mitochondrial enzymes, that is, it has a direct effect on the combustion of fats in the mitochondria of muscle cells. Considering also the fact that its deficiency was found in almost half of the patients suffering from obesity, its use plays a significant role in the process of treating this disease. Not unimportant and the positive effect of Q10 on the skin. Usually in people who are losing weight, especially those who are not young, the skin is not elastic enough, which is manifested in the formation of numerous wrinkles and skin folds. In order not to be ultimately like a “Shar Pei”, one should worry in advance about nutrition and normalization of the skin condition. Kuenzyme Q10 is a natural substance necessary for the production of cellular energy, which stimulates the cells in the deep layers of the skin. He is involved in the metabolism, provides a process of regeneration in the upper layers of the skin, making it more elastic and smooth. Combined external and internal use of Q10 preparations is recommended, since only with local use Q10 affects the most superficial keratinized skin layers, and deep-lying living layers turn out to be unattainable. Supplementing Q10 is particularly important given the fact that under the effect of restricting the diet, its content in skin cells drops sharply. As a result, the amount of lipid peroxides increases, the structure of the skin is disturbed. Santegra® company offers a high quality product - CoQ10, containing the recommended amount of coenzyme Q10 - 30 mg. Take Q10 with meals to ensure maximum absorption. It is soluble in fats, and therefore its absorption increases significantly when taken with food containing fats, especially vegetable oils (Omega 3).
8. Moxonidine (Physiotens) The ability of the hypotensive drug Physiotensa (moxonidine) to improve metabolic parameters, while reducing arterial pressure, makes it the drug of choice for treating patients with arterial hypertension against the background of overweight and metabolic syndrome. In multicenter clinical studies involving almost 4,500 patients, Physiotens, in addition to the hypotensive effect, contributed to a significant reduction in body weight. The effect of Physiotensin depended on the degree of obesity in patients - no weight loss was observed in patients with normal body weight, and, conversely, in patients with degree 3 obesity, the effect of moxonidine was maximum. British scientists have proven these effects of Physiotens experimentally. It turned out that moxonidine reduces food intake and body weight in genetically obese, hypertensive Zucker rats. These experimental data are another confirmation of the most rational choice of Physiotens (moxonidine) in the treatment of patients with hypertension against the background of overweight.
9. Garcinia cambogia - Garcinia cambodgia is an evergreen tree of the family of mammals. In South Asia, Garcinia fruits have been used for centuries in cooking. It is believed that adding garcinia makes the food "more satisfying and satisfying." Garcinia cambogia contains hydroxycitric acid (GOC-citrine), which reduces the formation of new fats in the body, affects the oxidation of fats by increasing the formation of endogenous carnitine and partially regulates appetite. Биохимический механизм этого процесса следующий: гидроксилимонная кислота, имея близкую структуру с лимонной кислотой, образующейся в клетках нашего организма, угнетает активность фермента цитратлидазы и тем самым по конкурентному типу подавляет образование ацетил-КоА, что, в свою очередь, ограничивает дальнейший синтез жирных кислот через малонил-КоА. В то же время под действием ГОЦ-цитрина происходит активация фермента карнитинацилтрансферазы, благодаря чему активируется образование карнитина и, соответственно, усиливается транспорт внутриклеточных жирных кислот в митохондрии и их окисление в этих субклеточных образованиях. Регулирующее влияние ГОЦ- цитрина на аппетит заключается в его опосредованном влиянии на активность нейронов гипоталамуса, отвечающих за чувство голода и сытости. Блокируя образование жирных кислот из углеводов, он поддерживает такую концентрацию глюкозы, при которой нейроны гипоталамуса не стимулируют аппетит. При обычной дозировке гарцинии камбоджийской аппетит подавляется на 43% на протяжении 6,5 часов и на 29% на протяжении 24 часов. Лучше принимать гарцинию за 30 минут до еды.
10. Последние десятилетия широко применяются для лечения ожирения лекарства, действие которых основано на коррекции серотонинового обмена (стимуляция высвобождения норадреналина и серотонина и ингибирование их обратного захвата). Влияние на серотониновый обмен оказывает успокаивающее действие и уменьшает аппетит, поэтому данные препараты значительно снижают гиперфагию (т.е. переедание). По химическому составу это дериваты амфетамина, фенфлурамин, дексфенфлурамин, фенилпропаноламин. По названиям это «Изолипан», «Минифаж», «Тримекс», «Диетрин». Идея снизить вес под воздействием на определенные рецепторы головного мозга ненова. Однако многие производимые ранее лекарства этой группы вызывали лекарственную зависимость и имели много побочных эффектов. Исключение составляет новый препарат «МЕРИДИА MERIDIA» (сибутрамин), разработанный немецкой фирмой «Кнолль АГ». Механизм действия этого препарата заключается в том, что он физиологично воздействует на специфическую область головного мозга, тем самым способствуя появлению чувства насыщения. Благодаря этому становится возможным снизить количество потребляемой пищи. Подавляется желание съесть что-нибудь сладкое или перекусить между приемами пищи. Это актуально только в первые несколько дней прохождения методики, во время которых организм адаптируется к новому режиму питания. Обычно я назначаю этот препарат в самом начале на очень короткий срок, не превышающий двух недель, но очень часто многие мои пациенты перестают принимать его самостоятельно гораздо раньше. Это зависит от индивидуальных особенностей организма, его способности к адаптации. Хотя я часто использую этот препарат в своей практике, и на собственном опыте убедился в его эффективности и безвредности для организма, следует все же помнить, что «МЕРИДИА MERIDIA» это лекарственный препарат, а не пищевая добавка. У него есть определенные противопоказания. Его нельзя принимать самостоятельно! Для этого необходима консультация и назначение врача!
Применение перечисленных препаратов на разных этапах прохождения методики делает ограничения питания легко переносимыми и не мучительными. Они позволяют не только «сидеть» на низкокалорийных и ограничительных диетах, но так же уменьшают углеводную жажду, умеряют аппетит, улучшают и поправляют измененный обмен веществ организма. Но верить в то, что препараты для похудания все сделают за Вас без каких либо усилий с Вашей стороны так же наивно, как верить в вечную любовь или всеобщее равенство.
Я часто настоятельно рекомендую всем своим пациентам, после моих назначений, самостоятельно, изучить информацию о предлагаемых препаратах. При этом я подробно объясняю механизм действия каждого из них, и обосновываю необходимость в их применении.
Если же ориентироваться только по тому, что пишут на этикетках этих препаратов, может сложиться представление, что все они нам крайне необходимы.
Еще и еще раз хочу подчеркнуть, что любые препараты, используемые в процессе лечения ожирения, являются только необходимым дополнением к целому комплексу основных мер. БАДы - только подспорье в святом деле усовершенствования фигуры. Полагаться на них целиком и полностью не стоит. Когда реклама обещает, что препарат все сделает за вас без ограничений в еде и физической нагрузки, причем без ущерба для здоровья - не верьте!
В заключение этой темы, хочется сказать,- я рад, что люди недоверчиво и творчески подходят ко всем новым препаратам для похудания. Стараются найти объективную информацию об этих препаратах. Но чаще всего, полученные таким путем знания все равно не заменят опыта и знаний врача. Поэтому я бы несколько изменил старую поговорку - «Проверяй, но доверяй»!
<< Ahead Next >>
= Go to tutorial content =

Вспомогательная медикаментозная поддержка.

  1. Вспомогательная вентиляция легких с поддержкой давлением
    Одним из эффективных и широко используемых методов ВВЛ является вентиляция с поддержкой давлением — ВПД (Pressure support ventilation — PSV, или просто Pressure support — PS, а также Assisted spontaneous breathing — ASB). Сущность этого способа заключается в поддержке каждого самостоятельного вдоха быстрым созданием в дыхательных путях заранее заданного положительного давления. При инспираторной
  2. Медикаментозная поддержка при проведении перкутанного коронарного вмешательства. Ведение больных в ранний и поздний период после стентирования
    До проведения процедуры рекомендуется болюсное внутрикоронарное введение нитроглицерина, что позволяет оценить истинные размеры сосуда и снизить риск вазоспастической реакции во время процедуры (Рекомендации для нитроглицерина: I С). Введение нитроглицерина можно проводить повторно во время процедуры или после нее, учитывая показатели АД. В редких случаях вазоспазма, резистентного к
  3. Respiratory support in acute respiratory distress syndrome, the concept of "gentle" mechanical ventilation, auxiliary methods of oxygenation
    One of the most difficult tasks of respiratory support is to perform mechanical ventilation and internal radiation in acute respiratory distress syndrome (ARDS), which is known to have persistent, poorly corrected hypoxemia, marked irregularity of the lung lesion, frequent development of complications - lung tissue barotrauma, joining nosocomial
  4. Медикаментозная зависимость
    Причина Медикаментозную зависимость способны вызывать не только препараты с психотропной активностью (наркотические анальгетики, психостимуляторы, транквилизаторы), но и другие лекарственные препараты при их постоянном приеме. Основой формирования такой зависимости является способность многих препаратов изменять психическое состояние человека, влиять на настроение, уменьшать тревогу, страх,
  5. Медикаментозная терапия
    Для медикаментозного лечения в гинекологии чаще применяются антибактериальные, кровоостанавливающие, обезболивающие средства, иммунокорректоры, биостимуляторы. Обезболивающие средства в гинекологии используются для симптоматического лечения при болях после операции, заболеваниях с выраженным болевым симптомом (онкология, альгодисменорея, эндометриоз, воспалительные процессы и др.). For
  6. Медикаментозная терапия
    В ранних, начальных фазах заболевания лечение очень эффективно и под воздействием соответствующих процедур все болезненные симптомы быстро исчезают. Если болезнь запущена, выздоровление наступает медленнее и требует применения целого комплекса лечебных мер, который включает в себя физкультуру, физиотерапию и применение лекарственных средств. Медикаментозная терапия в лечении ВСД по
  7. Percutaneous Coronary Interventions and Drug Treatment
    A meta-analysis of randomized controlled trials showed that percutaneous coronary interventions, as compared with medical treatment, lead to a more pronounced reduction in the symptoms of angina pectoris. At the same time, the studies did not include a sufficient number of patients for an informative assessment of the effect of percutaneous coronary interventions on the subsequent development of heart attacks and deaths.
  8. Drug treatment of CHF with systolic dysfunction of the LV
    GENERAL COMMENTS Pharmacotherapy is the main therapeutic approach for CHF. Given the progressive nature of the latter, medical treatment of patients should be carried out throughout their life and be monitored (that is, evaluated and properly adjusted) by a doctor. Today, a detailed algorithm has been developed for treating patients with CHF and LV systolic dysfunction, as
  9. Medical component of neuroprotective therapy
    Currently, there are numerous targets - the key links of the mechanisms of disorders developing during cell hypoxia. Accordingly, these “targets” have created, apply and continue to create numerous medications with neuroprotective properties (Table 2). Table 2. TARGETS OF MEANS OF IMPACT Violation of the neuron energy supply Macroergs, metabolics
  10. Медикаментозная тахикардия
    Препараты наперстянки ввиду особенно частого их назначения имеют наибольшую вероятность индукции желудочковой аритмии. Подобным нарушениям ритма нередко предшествуют симптомы общей интоксикации, но иногда их могут опережать сердечные эффекты. В некоторых случаях первым проявлением бывает бигеминия, обусловленная регулярными желудочковыми экстрасистолиями; другим серьезным признаком может быть так
Medical portal "MedguideBook" © 2014-2016
info@medicine-guidebook.com