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Інфекційна катарана Гарычка's a sheep
Infectious catarrhal hot sheep (Febris catarrhalis infectiosa ovium, blutang, blue tongue) is a viral transmissible spruce, which is characterized by wild grasses, fired necrotic infections of mucous membranes of grass, as well as In zvyazku with the characteristic izmerennyas of the tongue of twig distal I will call “blue tongue” or “black mouth”.
Istorichna dovidka. Blossom on top of Bulo was registered in 1876. at Pivdenny Africі. The hindrance of an infectious catarrhal garyachka guarded the sheep of the midship, and often passed asymptomatically. However, the introduction of the sheep from Europe to Africa (1852 - 1870 r.) Brought the spruce into a wicked character and shvidko spread across the whole continent. Ninі іnfektsіyna catarrhal garyachka to become serioznu iz_izootologіchny і economically problem in usuvomu svіti.
First, twisting and twisting I described Hutchin (1881), and having established the nature of Teiler (1906). Sprewell (1901), having expelled the method of immunization of sheep with virulent blood and that of immune syrovatka, and Teyler (1907), after having wiggled atenuovanu, I live the vaccine. In 1947 p. Alexander izolyuvav virus at smoking embries.
For the remaining 60 years of catarrhal catarrhal, the hot sheep sheep fought even more in the country of Africa, as well as in Palestine, Syria, Iran and Turechchin. In 1948 p. twig Bulo was registered in America, in 1956 - on the portugal of Portugal in Spain, in 1959 - at the Schedule of Pakistan and Japan, in 1946 p. - in Іndії. For the tributes of the International Epizootic Bureau, an infectious catarrhal garyachka was installed in 40 countries of the world, however, it was 45 ° Mon. w. not registered. To save money on animals, such as planting twigs, they are represented by a high degree of illness (10 - 50%) and mortality (90 - 100%) by creatures, lower productivity of sheep, and vitamins for organizing visits. Infectious catarrhal garyachka sheep was presented to the group A, I want to inform me and introduce MEB and introduce mezhmezhna to trade in meat and, at least, that is thin.
Twig Arbor - RNA genomic virus, which can be found before the homeland of Reoviridae, the genus Orbivirus. Vіrіoni may have a spherical shape, diameter 65 - 80 nm, two icosahedral capsidi, 7 structural bіlkіv. Vidomo 24 serotypes to virusu, so as not to assimilate the sheep of a superlative imunetu. Vіrus avenged in blood, blood and plasma, in blood-forming organs, hour of burning - in spleen, liver, lymph nodes. In the period of supreme clinical signs, the virus is localized in the mucous lining of the intestines, epithelial and mnous tissues. Virusemia in sheep’s trousers for sale 35 - 49 db for writing, independent of manifestation in blood virusneutralіzuyuchih antibodies. Virus is cultivated in smoking embryos of 6–8 days old or 11–13 days old, in organisms of new-born birch larvae are targeted, in the first cultures of klitin nyrok lambs, aboembrya bovines, as well as in skeletal lamb, 21 klnin Helin.
After 2 - 3 dobs of infection, the CPD is declared: rounded klitin, granularity, assimilation of internal plasmatic (RNA-positive) and internal nuclear (DNA-positive) inclusion, fragmentation of the monitory ball. From laboratory creatures to virus, 1–4-day-old targets are targeted, as well as homies.
Vіrus to finish the old one at the middle one. In carcasses, sheep at a pH not lower than 6.3 ° C and at a temperature of 4 ° C can be varied up to 30 dB, in the blood, conserved in the food of Edison, and at room temperature there will be a loss of food for 25 days. It is resistant to low temperature and must be stored in the frozen to -70 ° C sperm. Heated to 60 ° C ruinu virus after 5 hv, at 37 ° C and pH <6 virusinaktivuetsya after 1 chv. Під дією 3% reason for formalin virus guinea after 48 - 72 years, 3% reason for pure sodium and 70 ° ethyl alcohol - after 5 cu.
Epizootology twig. To the ridge of infectious catarrhal gum in the natural minds of quick and small - the horn of thinness, goats, antelopes, elk, American birch tails deer, snigov vіvtsі is great. Particularly sensitive are the lambs. At the stationarily disadvantaged points of the Sisuni lambs, they pass on a passive and do not sick. Dzherelom zbudnika Інфекції є illness and rebuilding vivtsi, scho me to become virusonosіami for sale 3 - 4 ms. Moved to virus vid to bring healthy creatures to healthy health Molecules Culicoides, which are characterized by significant expansions and great numbers, as well as mosquitoes Aedes and Melophagus ovinus. Naibіlsh a significant reservoir of virus in nature to respect the great horned thinness, in the body of a certain virus to be protected until the offensive active period of the cycle of developing pathetic comas. Through the middle lanka, through the yak it is also possible to pass to the virus to the fastest to the virus, to be able to buti wild juvenile creatures and grisuni. The contact hole can not be transmitted.
Інфекційна катарана Гарычка's a sheep, it’s characterized by seasonality, and it’s possible to take advantage of the period of visits and the most active transfer coma. Epizootic twigs span in the lower reaches, behind the flow of rivers, along the banks of standing waters.
Creatures become infected at different times of the night, but early-wrants. In dry rocky, the dry season, hot year of the day, when the sheep are exterminated at the primaries, as well as in the Girsky zones, there is no way to catch up. An infectious catarrhal garyachka to pass at a place of great importance and with great numbers of populations (50 - 60%), is characterized by severe excesses and a high mortality rate, with a maximum of 90% of them, and 30%.
The pathogenesis of infusion is not enough. Pislya penetration into organism vіrus reproduced in the blood and zoom trivial protopasnitsyu.
With the development of the clinical picture, the virus is located in the glands, the lymph nodes, the liver, and the localized in the mucous membranes of the intestines, the natural and small tissues. Reproduction of virus in the organs and tissues of the brain zoom in the amount of rechovin, increased penetration of the sudin, development of glow-degenerative and necrotic manifestations, erosion and virazok. The abortion of the fetus and embryo wiklik є abortion, the birth of undead-giving young. In the case of creatures, the resistance to organism is lower, the second is bacterial infection, which can lead to a significant acceleration of the pathological process and the death of creatures.
The special infection process in the case of an infectious catarrhal sheep є trial (for sale months) is persistent in blood, independent of the fact that it’s possible to receive the highest possible title.
Clinical signs and interruptions of twigs. Іnkubatsіyniy perіod trivaє 2 - 6 dib. Perebіg a twig of guests and a guesthouse. Appear as an abortive form of twigs. From time to time, you can speed up the temperature and temperature up to 40.6 - 42 ° C, and yakatryutsya on the whole river with a length of 6 –12 dB. Immediately, I’m convinced of the pride, I’m not sure of the tune to go, I’ve captured the vіdstayut vіd of the herd.
After 24 - 36 years, the temperature of the body develops, the catarrhal inflamed mucous membranes of the mouth, tongue, pharynx, and nasal empty. There is a head outfit, a tongue waving in ob'єmi, a waving blue-red darling, a name for a twig called “blue tongue”. Protein blueprint of a language may not be but after 1 - 2 dobnik znikaє. At the same time, we’ll see the image from the mouth of the pineal slug (“vologa muzzle”), see the old, impeccable flanks of the tongue, and also the nose, the watery and the mucous. Virazkovy abo gangrenous stomatitis develops, the passage with blood houses is declared.
At the rear end there is a little redness and swelling of the end, of the parts to ratify, pain in the onslaught.
In bagatokh tvrin, you can speed up your culture, “sound” on the go, on school’s activities, you can learn more and more, wool. Creatures lose weight i on the 7th - 8th dobu twigs to drive. Lethality can reach 70 - 90%. Viduzhuvannya is now better, not earlier than in 10 - 15 days to lower the temperature. In lambs, pneumonia develops, accelerated by necrobacteriosis, but even 100% of deaths result in death.
Pid hour p і d g about with t about r about stopping for a while so much as you can get the same number of signs, as if at gostroma, however, the severity of their turn is much less. Triviality of twigs - 12 - 25 db, lethality to become 20 - 60%. And the abortion form of the twig manifests itself more unnecessarily with a short-hour garyachkoy, maw, superficial catarrhal burners of the mucous membranes of the buccal cavity, conjunctivitis. Oduzhannya nastє porivnyano shvidko. When there is anorexia, salivation, hyperemia of the mucous membranes of the oral nasal cavity. On the nasal dzercaltsі, lips, yasnas, vimenі, vulva there are virazas, bloodsuckers. The tongue is very swollen, it hangs out of the mouth, it’s a lot of hard work, and the thinness of the guinea wards. INODI sposterіgayutsya abortion, the birth of undead indifferent offspring. In the endemic episodes of overcoming the twigs of a great horned thinness, they often become asymptomatic, with trivial virosonism.
Pathologist zmіni. The corpses are visually impaired; Pіdshkіrna klіtkina і mіzhm'yazova is completely fabric in dulyany heads, shiі, back nabryakly і, іnfіltirovanі zhovtuvatoyu іdinoyu. Nabryaki can also be found in the middle of the open spaces, pharynx, larynx, tongue and lips. On the tongues, lips, inner surface of the cheek, the bloodshed are viral.
Selezіnka significantly zbіlshena in volume. Lymphatic nodes, especially deepthroat, halfhearted, shiiny and mezenterialny, zbіlshenі, gіperemіyovanі, nabryakly. In breast and empty cows, the accumulation of a dragged exudate with blood houses can be spelled out. On the surface of the leg, the mucous membranes of the grassy canal and the dichal grooms, the capsule of the liver and the spleen, the epicardium and the endocardium are manifested in bloodshed.
The diagnosis is established on the basis of epizootological data, clinical signs of twigs, pathological anatomical signs and results of laboratory tests.
Laboratory diagnostics. The transfer of information from pathological materials to the virus, identification and identification of additional neutralization reactions (for smoking rooms and culture) for RIF, RZK, RDP, and other types of blood donations. In the case of large vipads, conduct a test on lambs.
For survival, send blood samples to the laboratory, take samples at the same time as the temperature of the sheep, and for post-mortem diagnosis, don’t have to pay attention to the deadline.
In order to see the virus, it is necessary to carry out infection with the pathological material in the Zhovtokovy bear of 6 - 8-day-old smoking embryos, or in the judge of the KhAO 11 - 13-day-old smoking embryos. The specific death rate of infected embryos is present in 4-8 and 3-4 extras.
At times, for the view of the virus of cultural cultures, it is necessary to have 2 to 4 passages, first and lower because of the characteristic cytopathogenic nature of the monosphere. Identification of the virus is recognized for the additional neutralization reaction in the cultural culture, as well as for smoking embankments with an undeveloped specific syrovatka, as well as for the auxiliary RIF, RZK and RDP.
Identify serotype virus by plaque pH and the plaque method using agar monochromatic virus infected with Vero culture virus. A biological test should be carried out on 1–4-day-old targets, infect them intracerebrally, as well as on lambs of a 3–6-month-old infant, and some pathological material should be administered internally, internally, or abnormally.
Characteristic clinical signs of twigs appear after 6 to 8 days and appear in the elevated temperature, hyperemia of the mucous membranes of the mouth and nose, swollen lips and tongue. Experimentally infect lambs before being infected and after 21 - 30 days, if they are infected, they will collect shelter and receive for RZK. Appearance of specific complementations of juvenile antithesis about the manifestation of the material of the virus. Serodiagnosis and retrospective diagnostics of infectious catarrhal fumes of sheep should be carried out for the auxiliary RZK, RDP, RZGA, RN, and at times there are also RRH, RIF and ELISA methods. At the same time, the convalescents of convalescence to reach RZK, for which it is possible to display group-specific antibodies against all serotypes of the spruce. Complementary antithesis is detected in blood after 2 hours of infection in credits of 1: 4 - 1: 16 and reach the maximum indicators (1: 60 - 1: 256) for the 30th add.
Differential diagnosis. Transmission of the need for exclusion of foot and mouth disease, contagious ectimies, sheep and cat, vesicular stomatitis, vispi, necrobacteriosis, Nairobi twigs, and rhizomes of the Rift valley. Foot and mouth disease, contagious ectima sheep and kiz, and vyspa sheep are characterized by a high contagiousness, their belts are not tied to sometimes with a massive amount of bloodsucking coma. For foot-and-mouth disease, the characteristics of aphthous and abdominal emptying, vimen, kintsovok; important results of higher education. In case of contagious knowledge, specific pustulenny izmerenniya mucous membranes of the oral cavity and shkirnogo shave in dilyansa puta, vіnchika, mizhratitsovo schіlini. The hour of microscopic inspection of dry smears and dry non-conserved scabs will show the appearance of the twig. Foot and mouth disease and vesicular stomatitis are differentiated on the basis of the results of RZK with antigen and antigen vesicle ill. To conduct a bioprobe on rabbits and lambs. Please note that the following microscopic results are paid for by Morozov’s brushwork on the inside of the upper papules and on the background of the same preparation of brown and dark colored items. When there is a risk of infection, it is overwhelmingly defying, in the pathological material you will see the spruce furrow Fusobacterium necrophorum. Twig Nairobi superconducted by the abdomen of hemorrhagic diathesis and severe gastroenteritis. For the Lyhomanka Rift Valley, there is a characteristic degeneration of the liver and middle necrosis. The residual diagnosis should be established for the results of laboratory tests.
Likuvannya not scattered.
Imunetet. Overwhelming creatures to inculcate their immunity against that type of virus, having caused a twig. Mozhliva reinfektsiya _nshim type virusu for sale that very season chi offensive rock.
Active immunity in convalescence is superconducting to assimilation of neutral and complementary antithesis, and passively transmitted to young animals with colostrum. In dysfunctional countries for specific prophylaxis of infectious catarrhal garyachki, sheep and sheep are alive and inactive vaccines. Imunitet and specific antibodies at high credits zbirigayutsya after vaccination is not less than one rick.
Prevention and come on. Infektsіyna catarrhal garbage in our country is not registered. I’m grounded in the main respect for keeping in secret for importation of imported svіyskimi (vivtsi, goats, great horned thinness) and wild creepy creatures. Obov'yazkovim є prophylactic quarantine of all imported creatures at the time of consumption at the same time and serological doslizhen. In dysfunctional countries, come in for prevention and treatment of ill health and health with veterinary legislation.
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