Licensed books on medicine
<< Ahead || Next >> |
Disorder of sexual function associated with metabolic disorders (nutritional impotence)
Etiology. Occurs in manufacturing bulls with protein overfeeding (the content in the diet is more than 50% of concentrated feed for the overall nutritional value), lack of carbohydrate in the diet (sugar-protein ratio less than 0.8: 1.0), vitamins (for 1 cu. less than 70 mg of carotene, 1500 IU of vitamin D and less than 40 mg of vitamin E), mineral substances (1 kg of calcium less than 7 g, phosphorus - 5 g, sodium chloride - 8 g, potassium - 19 g, magnesium - 5 g), as well as with a lack of trace elements (iodine, cobalt, zinc, copper, manganese, iron, etc.), feeding poor quality x feed and feed containing impurities of fluorine, arsenic, salts of heavy metals, keeping animals in poorly lit and insufficiently ventilated areas, in the absence of active daily walks.
Symptoms and course. Metabolic disorders manifest as endogenous toxicosis, acidosis, ketonemia, ketonuria, hyperproteinemia, hypoglycemia, diseases of the ligament tendon and bone apparatus (osteodystrophy), accompanied by disorder of biosynthesis, incretion and metabolism of sex hormones.
The initial stages of the disease are accompanied by the appearance of weakness and some pain in the hind limbs and a decrease in sexual activity. Clinical signs of impaired sexual apparatus may be absent. However, the germinal epithelium of the seminiferous tubules undergoes degenerative changes, which entails a violation and inhibition of spermatogenesis. The volume of ejaculate is reduced by 10-20%, the activity of sperm decreases to 6-7 points, their absolute survival rate to 1000 units. and less, dehydrogenase activity up to 20-25 tons, the number of pathological forms of sperm, especially those with defects of the tails, increases to 15-20% and dead to 15-25%. In the blood of such animals, the content of ketone bodies increases to 7-10 mg / 100 ml, estradiol - 17 beta to 45-60 pg / ml, the glucose content decreases to 36-38 mg / 100 ml, total calcium to 8-9.5 mg / 100ml, inorganic phosphorus up to 3.8-4 mg / 100ml, vitamin A up to 20-25 μg / 100ml, testosterone up to 1-3 ng / ml, alkaline reserve up to 40-45% vol. CO2. The content of ketone bodies in the urine is increased to 20 mg / 100 ml, total serum protein to 9.5-12 g / 100 ml. In some cases, there is a decrease in the amount of protein in the blood to 7.5 g / 100 ml.
With prolonged exposure to adverse factors and clinically expressed forms of metabolic disorders (osteodystrophy, ketosis, obesity), diffuse degeneration of the germinal epithelium of the seminiferous tubules develops in the sex glands of manufacturers.
Seed plants can maintain normal size, smooth surface, mobility, however, lose their elasticity and acquire a soft texture. There is a decrease in sexual activity, a weakening of the sexual reflexes and a significant deterioration in the quality indicators of sperm. The volume of ejaculate and sperm concentration is less than 6 points, the survival rate decreases to 400-600 units, dehydrogenase activity to 30 minutes or more, the number of pathological and dead sperm cells increases to 25-30% or more.
Subsequently, blood biochemical indices can level off, and the quality of sperm production remains low (oligospermatism, oligospermia, teratospermia, necrospermia).
Disruption of metabolism and reduction of sexual potency in manufacturing bulls may also be associated with adverse effects on their bodies of technologically unavoidable stress factors (operational, vaccinal, emotional and painful, climatic), accompanied by increased costs of plastic, energy resources and biologically active substances.
Treatment. To restore the impaired reproductive function of the manufacturing bulls, first of all, they correct the diets of animals, taking into account the norms of need, quality and chemical composition of feed, and organize active exercise. Animals additionally prescribed vitamins and microelements. For the first 7-10 days, for every 100 kg of body weight, vitamins and trace elements are fed: A - 70-80 thousand IU, D - 7-8 thousand IU, E - 70-80 mg and C - 250-300 mg, B1 - 0.05-0.06 mg, B2 - 0.4-0.5 mg, B12 - O, I-0.15 mg, copper sulphate - 100-150 mg, zinc sulphate - 250-300 mg, manganese sulphate - 300-400 mg, cobalt chloride - 6-10 mg, potassium iodide - 1.5-2.0 mg. Iodine is used in a stabilized form. In the subsequent periods of biologically active substances prescribed in half doses to normalize metabolism and reproductive ability of bulls. Against the background of a normalized metabolism, it is advisable to use twice the purified gonadotropin FFA at a dose of 4 mU / kg with an interval of 2-3 weeks.
| << Ahead || Next >> |
| = Go to tutorial content = |
Disorder of sexual function associated with metabolic disorders (nutritional impotence)
- Dysfunction of the nervous system caused by hereditary metabolic disorders
Disorders of the nervous system in congenital metabolic disorders result from the influence of several factors: • direct damage to nerve cells due to the lack of any enzyme; • accumulation of certain undigested metabolic products outside the cellular fluid; • damage to other organs (eg, liver); • damage to cerebral vessels.
- Metabolic disorders and physiological functions during hypoxia
Disbolism and physiological functions caused by a lack of oxygen supply, progressing with the insufficiency or exhaustion of compensatory-adaptive reactions. Initially, metabolic disorders manifest themselves in a decrease in the synthesis of high-energy compounds and changes in carbohydrate metabolism. Glycolysis, glycogenolysis are activated, production of pyruvate and lactate increases;
- Violations of the main physiological functions and metabolism
The nervous tissue is most sensitive to oxygen starvation. With the complete cessation of oxygen supply, signs of disturbance in the cerebral cortex are already detected after 2.5-3 minutes. In acute hypoxia, the first disorders (especially clearly manifested in its hypoxic form) are observed on the part of higher nervous activity (euphoria, emotional disorders, changes in handwriting and
- Disorder of sexual function and disease of the male genital organs
In manufacturing bulls, sexual dysfunction is most often associated with metabolic disorders and neuroendocrine regulation of sexual processes, manifested in a decrease in sexual activity, weakening or inhibition of sexual reflexes, spermogenesis, a decrease in the quantity and quality of sperm production, as well as inappropriate use and in some cases inflammatory processes in
- Heart damage in metabolic disorders
Metabolic disorders in the body always affect the course of metabolic processes in the myocardium, often causing a violation of its function and structure. In various diseases, one or several pathways of metabolism may be initially disturbed, which further necessarily affects the energy supply of the heart muscle. With some metabolic disorders in the interstitial myocardial tissue and in
- Special treatment of metabolic disorders
Metabolic disorders in diabetes, regardless of the various pathogenetic aspects, are based on insulin deficiency. Diet, muscular work and the use of insulin and perorial antidiabetic drugs for more than 20 years are the basis of treatment in each case. Treatment methods Oral diabetes therapy, medications, see table. 25. Insulin: Drugs Used
- Disorder of the neuroendocrine regulation of sexual function in manufacturing bulls
Etiology. Technological stress caused by injections of biologically active drugs (allergens, vaccines) and the formation of specific immunity, pain effects (puncture of the jugular vein, fixation of animals when treating hoofs, etc.), as well as changing personnel, technological methods, movements of animals, has a favorable prognosis . However, in the first 5-7 days after
- SUBSTANCES DISORDERS
DISORDERS OF EXCHANGE
- Sodium metabolism disorders and osmolality disorders
Despite the fact that the amount of sodium and water entering the body varies widely, the circulating blood volume, sodium content and plasma osmolality in healthy people remain very constant. An increase in plasma osmolality causes thirst and increased secretion of antidiuretic hormone (ADH) by the pituitary-hypothalamus system. ADH then acts on the collecting duct of the medulla
- Features of metabolic disorders in the outbreak of inflammation
The development of alterations, vascular changes in the area of inflammation naturally combined with typical disorders of metabolism. First of all, it should be noted a sharp increase in metabolism at the stage of arterial hyperemia due to increased oxygenation, increased activity of glycolysis enzymes and aerobic oxidation. In the experiment, it was shown that oxygen consumption at the same time increases by
- CONSTRUCTIVE SUBSTANCES DISORDERS
A rare disease commonly seen in Siamese and American Shorthair cats. The disease is caused by the absence of one or several key enzymes necessary for the normal functioning of the nerve cells, and is inherited in a recessive manner. That is, for the manifestation of the disease in one or more kittens, both parents must be heterozygous for this trait. Get sick
- HOMEOPATHIC TREATMENT OF DISEASES OF DIGESTIONS AND DISORDERS OF SUBSTANCES EXCHANGE
Symptoms of digestive disorders are most frequent and occur in cats with decreased or no appetite, vomiting, diarrhea, or constipation. Most often, the process of digestion is disturbed in kittens when switching from one type of feeding to another, in long-haired cats because of periodically formed trichobezoar (lumps swallowed when licking wool) and in old animals as a result of
- VIOLATIONS OF THE MENSTRUAL CYCLE AND SEXUAL FUNCTION IN WOMEN
Bruce R. Carr, Jean D. Wilson (Bruce R. Carr, Jean D. Wilson) When changing the function of the reproductive system, women tend to complain of irregular menstruation, sexual function, pelvic pain or infertility. However, a single disease, such as uterine leiomyoma, may be accompanied by one or more of these symptoms. In addition, in violation of sexual function
- Dysfunction of the sex glands
Hypogonadism. Hypogonadism (hypofunction of the sex glands) is manifested either by inhibition of the function of the seminiferous tubules without disturbing the production of androgens, or by the insufficient formation of these hormones, or a combination of both processes. Castration. The most complete manifestations of hypogonadism develop after the removal of the sex glands. Pre-pubertal castration prevents the development of accessory
- ON THE USE OF THE PREPARATION OF HEMOVIT-PLUS IN DISTURBANCES OF THE EXCHANGE OF SUBSTANCES AND ALLERGIES OF VARIOUS ETIOLOGY IN CATS AND DOGS
I.N. Baklanova In our clinic, a new microelement drug hemovite-plus was tested on the basis of a complex of organic derivative of succinic acid with biologically active trace elements - Fe, Mn, Cu, Zn, Co, Se, I. The drug is included in the treatment regimen for diseases caused by the disorder metabolism and allergic conditions in dogs and cats. For three years in the clinic was observed over
- VIOLATIONS OF REPRODUCTIVE AND SEXUAL FUNCTIONS
REPRODUCTIVE AND SEXUAL DISORDERS