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Angina with leukemia
Various forms of leukemia are characterized by a progressive systemic disease of the hematopoietic tissue, in which foci of pathological hematopoiesis are formed in various organs, which eject immature leukocytes into the peripheral blood.
The disease is considered as neoplasia of the hematopoietic tissue, in which damage to the tissues of the pharynx can occur.
In acute leukemia, tonsillitis is one of the first manifestations of the disease in approximately patients. The form of angina can be very different. Catarrhal sore throat is accompanied by significant swelling of the pharyngeal mucosa, proceeds for a long time and does not respond to conventional therapy. Severely sore throat, such as lacunar or fibrinous, can occur, often with the development of ulcerative necrotic changes, sometimes combined with acute or subacute gingivitis, which occurs suddenly and is accompanied by a significant increase in body temperature.
Plaques in the throat are whitish and grayish-yellow, difficult to separate, leaving long bleeding areas. Swallowing is difficult, a putrid odor is felt from the mouth. Ulcerative necrotic manifestations usually indicate the malignancy of the course of acute leukemia, accompanied by hemorrhagic rashes on the skin of the extremities, sometimes in the form of extensive hemorrhages, most pronounced at the injection sites.
In chronic lymphocytic leukemia, hyperplasia of the lymphoid formations of the pharynx can be observed, which is especially significant at the height of the disease.
The increase in regional lymph nodes is more pronounced in the chronic form of the disease. Palpation of the lymph nodes are determined by test, painless. At the same time, an enlargement of the spleen and liver is often observed, which is especially pronounced in myeloid leukemia.
The blood picture is characterized by a high white blood cell count of 20.0 to 30.0-109 / L and above, often expressed by anemia. A leukopenic form of acute leukemia is possible when the white blood cell count drops to 1.0-3.0-109 / L.
The most reliable diagnostic sign of leukemia is the appearance in the blood of a large number of young and atypical cells (hematoblasts, myeloblasts, lymphoblasts).
Treatment is carried out under the supervision of a hematologist, care for the oral cavity and pharynx is necessary. In order to prevent secondary infection, antibiotic therapy is indicated. Assign cytostatics (atleran, dopan), corticosteroids, transfusions of leukocyte mass (100-125 ml each) or whole blood, x-ray therapy. The forecast is unfavorable, death occurs in the coming months.
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Angina with leukemia
- Differential diagnosis of angina Comparative signs of various forms of angina
- B-cell chronic lymphocytic leukemia / pro-lymphocytic leukemia / lymphoma from small lymphocytes.
These are similar neoplasms, characterized in that with chronic lymphocytic leukemia, tumor cells are found in peripheral blood, and with lymphoma they are not detected. Sometimes the second option is considered as an aleukemic course of leukemia. Chronic lymphocytic leukemia is more common in the age interval between 50 and 60 years and rarely occurs in people younger than 40 years. About 50% of all
- General disorders in the body with leukemia. Main causes of death
With leukemia, the following syndromes develop, often leading to the death of the patient: - anemic (inhibition of erythroid bone marrow growth); - hemorrhagic (bleeding from the gums, nose, intestines; hemorrhages in vital organs) - due to a decrease in the intensity of platelet production; - infectious (functional inferiority of leukemic leukocytes -
- The picture of peripheral blood in chronic leukemia
Chronic myeloid leukemia Chronic myelogenous leukemia is a disease of the hematopoietic system in which the precursor cell of myelopoiesis is affected. Etiology: in 85% of cases, a change in the chromosome set occurs - the so-called Philadelphia chromosome (Ph +) appears. The clinical picture I. Myeloproliferative syndrome: 1) general symptoms caused by intoxication, proliferation of leukemia
Angina is a common acute infectious disease in which local acute inflammation affects the lymphadenoid tissue of various tonsils of the pharynx. In the vast majority of cases, tonsillitis is tonsillitis, other tonsils are involved in the inflammatory process much less frequently. Therefore, in medical practice it is customary to mean the tonsillitis under the term “tonsillitis"
Training target: using diagnostic algorithms, be able to diagnose angina and its complications (paratonsillitis, paratonsillar abscess), determine the clinical form of the disease and prescribe adequate treatment; be able to conduct dispensary observation. Assignment for independent study of the topic. Using the textbook, guidelines and lecture material for the acquisition
Acute inflammation of the tonsils and pharyngeal mucosa. the term "acute tonsillitis" narrows the concept of "tonsillitis" and we do not recommend it. IN AND. Voyachek emphasized that it is necessary to pay particular attention to the defeat of the entire pharynx with angina. According to clinical data and pharyngoscopic picture, sore throats are divided into catarrhal, follicular, lacunar, ulcerative-membranous and necrotic.
- Sore throats
The clinical picture of Sore throat is infectious - diseases with the most pronounced local inflammatory process in the area of lymphoid tissue of the pharynx. Palatine tonsils are more often affected. Overcooling and other unfavorable factors leading to weakening of the body contribute to the disease. With catarrhal sore throat, the patient has malaise, fever, chills, headache
- Complications of tonsillitis
C onclusion of General and Complicated ana ng. The most severe and formidable are common complications, since they cause persistent damage to vital organs and systems of the body. Among them, in the first place (in frequency, but not in severity) rheumatism with its attacks and lesions of the heart and joints, often no less serious complications of tonsillitis in the kidneys,
Since tonsillitis is an acute inflammation of the tonsils, see the article ALMOND