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Features of the clinical manifestations of syphilitic infection

At present, dermatovenereology is experiencing certain difficulties in the diagnosis of syphilis, since syphilitic manifestations do not always correspond to the clinic previously described in the specialized literature. Taking antibiotics, self-medication, drinking alcohol, an unbalanced diet, the negative effects of environmental and other factors affect the immunological status, which contributes to the non-standard response of the body to the introduction of the pathogen and, naturally, to clinical manifestations on the skin and mucous membranes in patients with syphilis. The data of the literature and our clinical observations show that at present the features of the manifestations of syphilis are most often expressed in the form of the following symptoms.

1. The primary period of syphilis:

• the primary period of syphilis is most often manifested in the form of multiple erosive chancres;

• often a hard chancre is manifested in the form of small erosions, the so-called dwarf chancre;

• chancres appear simultaneously with regional lymphadenitis;

• phimosis and paraphimosis often develop from complications;

• rarely manifestations of polyadenitis; at the base of the chancre there may be no seal

2. Secondary fresh syphilis:

• in 90% of cases it is manifested by a roseola rash, in 59% - by a roseola - papular rash;

• solid chancre residues are detected in 59% of cases, more often in men

• (74%) and less often in sick women 43%);

• mild polyadenitis (in 29% of patients), the manifestations of which were noted in 62% of sick men and in 52% of women;

• palmar - plantar syphilitis is detected in 28% - 31% of cases;

• lesions of the anogenital area became more frequent (55%).

3. Secondary recurrent syphilis:

• in 85% of cases, papular syphilis is noted, and in 73% - rose-like rash;

• cases of similarity of clinical manifestations of secondary fresh and recurrent syphilis have become more frequent;

• palmar - plantar syphilis is detected in 46 - 50% of cases;

• every fourth patient has manifestations of polyadenitis;

• malignant forms of the disease became more frequent.

In recent years, the number of patients with secondary recurrent and early latent syphilis has increased.

Early congenital syphilis often proceeds in a latent form, with slightly pronounced manifestations.

In connection with the change in the clinical picture of untreated syphilis, especially with secondary relapse, conditions were created for diagnostic errors, which entails an inferior treatment of patients with syphilis.
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Features of the clinical manifestations of syphilitic infection

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