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Congenital syphilis. Fetal syphilis

Under the influence of treponem, changes that occur in the placenta make it functionally inferior, as a result of which its intrauterine death occurs at the 6-7th month of pregnancy. The dead fruit is pushed out on the 3-4th day, usually in a macerated state. The macerated fruit, compared with a normally developing fruit of the same age, has significantly smaller sizes and weights. The skin of stillbirths is bright red, folded, the epidermis is loosened and easily slides into vast layers. Due to the massive penetration of pale treponemas, all internal organs and the skeletal system of the fetus are affected. A huge amount of treponem is found in the liver, spleen, pancreas, adrenal glands.

Early congenital syphilis

Its manifestations are detected either immediately after birth, or during the first 3-4 months of life. In most cases, newborns with severe manifestations of early congenital syphilis are not viable and die in the first hours or days after birth due to functional inferiority of internal organs and general exhaustion.

Clinical signs of early congenital syphilis are detected on the part of the skin, mucous membranes, internal organs, musculoskeletal system, nervous system and generally corresponds to the period of acquired syphilis.

The appearance of a newborn sick with early congenital syphilis is almost pathognomonic. The child is poorly developed, has a small body weight, the skin due to the lack of subcutaneous tissue is flabby, folded. The baby's face is wrinkled (senile), the skin has a pale earthy or yellowish color, especially on the cheeks. Due to hydrocephalus and due to premature ossification of the skull bones, the size of the head is sharply increased, the fontanel is tense, the skin veins of the head are dilated.
The child’s behavior is restless, he often screams, develops poorly.

Lesions of the skin and mucous membranes can be represented by all varieties of secondary syphilis. Massive bone layers on the front surface of the tibia as a result of repeatedly recurring and ending with the ossification of osteoperiostitis leads to the formation of sickle-shaped protrusion and the formation of false saber-shaped tibia. In patients with early congenital syphilis, various forms of damage to the nervous system can be observed. The most typical form of damage to the organ of vision is damage to the retina and choroid — specific chorioretinitis. With ophthalmoscopy, mainly on the periphery of the fundus, small light or yellow spots are found, alternating with dotted pigmented patches.

Late Congenital Syphilis

Late congenital syphilis includes symptoms that appear 2 years or more after birth. The clinical picture of active late congenital syphilis is generally similar to the tertiary acquired. Reliable signs of late congenital syphilis arising from the direct effect of treponem on the organs and tissues of a child include parenchymal keratitis, specific labyrinthitis and Hetchinson's teeth.

Probable signs of late congenital syphilis include Robinson-Fournier radial near-mouth striae, true saber-shaped tibia, saddle nose, buttock-shaped skull, syphilitic gonitis.
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Congenital syphilis. Fetal syphilis

  1. CONGENITAL SYPHILIS. TREATMENT AND PREVENTION OF SYPHILIS
    The fact of transmission of syphilis to offspring was established in the late 15th - early 16th centuries. For several centuries, the question of the mechanism of transmission of syphilitic infection remained unclear. For centuries, the germinative hypothesis was dominant, according to which syphilis is transmitted to the fetus only by the father through a sperm that directly infects the egg cell. According to this view, a child with syphilis
  2. Tertiary syphilis. Congenital syphilis.
    Tertiary syphilis. Congenital
  3. Congenital syphilis
    Congenital syphilis (syphilis congenita) occurs due to infection of the fetus during pregnancy. In newborns, the development of acquired syphilis is also possible, which appears when a child is infected during childbirth. The source of infection of the fetus is only a mother with syphilis. The frequency of infection of children and the severity of congenital syphilis depend on the duration and
  4. Congenital syphilis
    C. BREAST AGE. Syphilis transmission to offspring occurs mainly in the first 3 years after infection of the mother. In the future, this ability weakens, but does not completely disappear (the "Kassovich law"). Treponema pallidum infects the fetus already at the 8th week of pregnancy, penetrating the placenta, the chlamydial, cytomegalovirus,
  5. Late Congenital Syphilis
    Late congenital syphilis (syphilis congenita tarda) occurs in patients who previously had signs of early congenital syphilis, or in children in whom congenital syphilis had not manifested before. The first symptoms of late congenital syphilis may appear 2 years after birth, but they usually do not develop after 30 years. S. T. Pavlov (1960) believes that most often late
  6. Congenital syphilis.
    Even during the first epidemic of syphilitic infection, it was noted that in addition to adults, children suffer from syphilis, and that the manifestations of syphilis in children are different from the manifestations of syphilis in adults. In Russia, syphilis was the scourge of the royal villages. These patients were not treated, they gave birth to sick children, who in turn had sick children. More than 400 years ago
  7. Diagnosis and prevention of congenital syphilis
    The diagnosis of congenital syphilis is established on the basis of: 1) the detection in a child of active manifestations of syphilis and positive serological reactions; 2) the mother has expressed manifestations of syphilis, or latent, asymptomatic syphilis, detected on the basis of positive results of repeated serological examination; 3) anamnestic evidence
  8. Late Congenital Syphilis
    Late congenital syphilis is considered by many authors as a relapse of syphilis, transferred in infancy or early childhood. Manifestations of late congenital syphilis are detected no earlier than 4-5 years of age, often at 14-15 years, and sometimes later. Lesions of the skin and mucous membranes in the form of tubercle and gummy syphilis do not differ from similar rashes with acquired
  9. Early congenital syphilis
    Typical changes in early congenital syphilis (syphilis congenita praecox) are detected no earlier than the 5th month of pregnancy. Syphilis of the fetus ends in its death at the 6-7th month of pregnancy. A dead fetus is born on the 3-4th day, in 80% of cases in a macerated state. The placenta afflicted with syphilis is larger, hypertrophied, flabby, fragile, easily torn,
  10. Congenital syphilis in infants
    Preterm birth in mothers not treated for syphilis occurs in 30% of cases, in those who received treatment in 16% of cases. Congenital syphilis in infants is characterized by damage to many organs and systems, so its symptoms are extremely diverse. The earlier the signs of the disease appear, the more unfavorable the prognosis and the higher the mortality rate. For most children
  11. Fetal syphilis
    Damage to the fetus, due to syph. inf, manifest heavy. changes int. organs and bone. sys. They are detected no earlier than V months inside. life and are associated with a massive penetration of bled chatter through the placenta. The greatest number of chatter is found in the liver, spleen., Adrenal gland. Affected parenchyma of the fetus is enlarged and becomes dense, which is associated with the development of diffuse proliferation. infiltration and subsequent
  12. Prevention of congenital syphilis
    Treatment of pregnant women is carried out in accordance with the diagnosis, make at least 2 injections of one of the benzathine penicillin preparations. The profile to lay down is carried out by 2-3 injections of an antibiotic of 2,400,000 units with an interval of 1 week. The prof-ka is provided with a 3-fold serologic survey of ber-x: in the 1st half of ber-ti (when attending an obstetrician-gynecologist. For registration by ber-ti) and in its second half (on
  13. Fetal syphilis
    As a result of the toxic effects of Tr. pallidum on the placenta in the 6-7 lunar month of pregnancy, the nutrition of the fetus is disturbed, which leads to fetal death and 3-4 days after death to a late miscarriage by a macerated fetus with low body weight. In the fetus, as a result of spirochetemia, all organs are affected in the form of specific diffuse inflammatory changes: small-cell
  14. Congenital syphilis
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  15. Early childhood congenital syphilis
    It is characterized by mild clinical symptoms. The clinical picture corresponds to the secondary acquired period of syphilis or a latent course may be observed. The clinic is dominated by large papules and broad warts, so some authors call this period condylomatous. The main features of the clinical picture of syphilis in early childhood 1)
  16. Late Congenital Syphilis
    Ingenic manifestations of syph. age later than 4-5 years from birth. Clinic: appeared tubercle-ulcerative syphilis and gum (skin of the trunk, limbs, face). The tubercles can group without merging. Tubercles and gummas can disintegrate forming ulcers, which are located on the mucus. about. the nose can perforate the nasal septum. Reliable signs are the Getchinson triad: keratitis, labyrinthitis, Getchinson’s teeth.
  17. SYPHILIS. PRIMARY PERIOD OF SYPHILIS
    Currently, there is a large group of sexually transmitted infections (STIs). Classification of STIs (WHO, 1982) Bacterial nature 1. Syphilis and other treponematoses (pint, frambesia, bezhel) 2. Gonorrhea 3. Chancroid 4. Venereal lymphogranulomatosis 5. Donovanosis 6. Urogenital chlamydia and Reiter’s disease 7. Urogenital mycoplasmosis (in t .h.
  18. The course of the secondary and tertiary periods of syphilis. Malignant course of syphilis
    Secondary period. This period begins with the onset of the first generalized rashes (on average 2.5 months after infection) and lasts in most cases for 2–4 years. The duration of the secondary period is individual and is determined by the characteristics of the patient's immune system. In the secondary period, the most pronounced wave-like course of syphilis, i.e., alternation
  19. Treatment of patients with syphilis. Cure criterion. Clinical examination of patients with syphilis
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  20. Syphilis
    Syphilis is a chronic sexually transmitted disease caused by damage to the skin, mucous membranes, internal organs, bones and nervous system. Congenital syphilis is an infectious disease, the infection of which occurred from a mother with syphilis in the period of fetal development. Congenital syphilis develops as a result of the pathogen entering the fetus through the placenta.
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